LAS X Life Science Microscope Software Platform
Do you struggle with a variety of instruments, protocols, and software interfaces in your lab?
Leica Application Suite X (LAS X) is the one software platform for all Leica microscopes: It integrates confocal, widefield, stereo, super-resolution, and light-sheet instruments from Leica Microsystems.
Serving your workflow
LAS X is made for every step of your research. This platform provides maximum ease of use and enables anyone in your team to become productive quickly. LAS X allows you to set up experiments, conduct them, and analyze their results. Using one platform for these tasks saves you time and helps ensure reliable results.
Save time, gain reliability
- See more with the image in the center of your screen
- Configure objectives and filter cubes within the software – no need to exit
- Save and recall your settings like acquisition parameters, configuration settings or interface layout for future experiments – for reliable reproduction of your experiments
Handle your data smoothly
Reviewing and displaying your data has just become easier:
- Select an object on the screen and view its highlighted measurement in the results table
- Use the Automatic Classifier to group your results
- Display and follow the particles’ trajectories over time
- Save the results with the experiment or create a report including histogram and binary mask
Complex made simple
LAS X supports you in analyzing even complex fluorescence experiments with ease.
- Create separate analysis channels for each fluorescent marker or color
- Assign an individual workflow to each
- Run an analysis of all aspects of your sample at the same time, e.g.
- Count the number of spots per nucleus
- Count healthy and abnormal cells in two separate channels
A quantum leap in high speed acquisition
The high speed linear motor stage offers absolutely precise positioning at previously unattainable speeds, e.g. 5 positions per second with a 40x objective. During acquisition vibration sensors detect when the stage stands still. The final results are razor-sharp images taken at the perfect moment, even when acquiring with maximum speed. This dramatic improvement is due to the optimal synchronisation between image acquisition and stage movement.
The Quantum Stage allows you to:
- Do high speed positioning with absolute precision (< ± 1 µm)
- Manually move the stage at any time while keeping the precise slide position tracked
Be in full climate control
With the Environmental Control module you can control all environmental data like temperature, CO2 or O2 conditions in one interface. All data is saved with the experiment.
- Monitor environmental data live or review it afterwards
- Run temperature profiles by using an acquisition macro
- Get a warning or automatically stop your experiment when parameters are out of range
Your pathfinder in image analysis
LAS X guides you through the analysis workflow, step by step.
- Get immediate feedback on the applied settings at each step through a viewer
- Get guidance from analysis wizards which lead you quickly to reproducible results
- Run automated analysis of multiple samples
GPS for your cells – the powerful navigation tool
Switch from searching image by image to seeing the full overview of your samples. Like a GPS for your cells, LAS X Navigator ensures that you always have a clear roadmap to brilliant data.
Create fast overviews of your samples and identify the important details instantly. Then set up high resolution image acquisition automatically using templates for slides, dishes and multiwell plates.
LAS X Core
Intuitive. Innovative. Indispensable
The LAS X Core Software has full image viewing capabilities, including annotations, image overlay and image comparison. It controls your Leica microscope. If you add a compatible Leica camera, you have a complete image acquisition station.
Acquisition and advanced modules complement LAS X Core software and boost your imaging and analysis capabilities.
*Please note that LAS X Core is not sufficient to drive a confocal system. Acquired data can be viewed, but no data can be acquired.
The power of LAS X in advanced life science research
Complex experiments require careful set-up and scrupulous execution. With LAS X you can be certain to elevate the impact of your work through its powerful features, focused on usability in every aspect. LAS X takes usability to the next level with a range of functions designed to facilitate you in your workflow.
- Run high speed experiments
- Analyze and review your data during image acquisition, e.g. FRAP, FRET, in LAS X
- Use the auto exporter function for external analysis and feedback into LAS X
- Create spectacular 3D rendered time lapse movies in real time during acquisition
LAS X Office for Widefield Research
With this LAS X Office version, you can view your images or analyze them, such as by making measurements and quantifications. By extending LAS X Office with separate licenses, then features like 3D visualization or image analysis can be enabled.
Download free LAS X Office for Life Science
Please note: This version does not offer any hardware control and cannot be used for image acquisition.
Raw widefield and THUNDER image representing a 3D maximum intensity projection of a 27.5 μm thick z-stack of Drosophila follicles. The THUNDER image was processed with LVCC. Green indicates aPKC and magenta Dlg. Images courtesy of Mark Khoury and Dr. David Bilder, University of California, Berkeley, USA.
