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Optical Coherence Tomography (OCT)

Leica Optical Coherence Tomography (OCT) systems support ophthalmologists, ophthalmic surgeons, and researchers with easy-to-use, high-quality imaging technology.

The preclinical OCT solutions provide insight into eye disease research, while the clinical OCT systems serve as an aid in diagnosing pathological conditions. Each system is non-invasive, contact-free, and helps detect and monitor morphological changes of ocular tissue.

OCT from Leica Microsystems

With the acquisition of Bioptigen in 2015, Leica Microsystems offers OCT imaging systems for clinical ophthalmology and preclinical research.

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Contact a local specialist for expert advice on the right OCT solution for your needs and budget.

EnFocus intraoperative OCT, built into the Proveo 8 ophthalmic microscope gives surgeons greater insights, immediate confirmation, and maximum freedom in the OR. Get an immediate visual confirmation of how sub-surface tissue reacts to surgical maneuvers in crisp high-resolution OCT imaging. 

Envisu clinical OCTOCT has become a standard in the clinic, the Envisu is our noninvasive, non-contact handheld solution that aids in diagnosis and monitoring of pediatric retinal disease from neonatal infants to adults.

About Optical Coherence Tomography (OCT)

Optical coherence tomography (OCT) is an imaging technology with applications in biology, medicine, and materials investigations. In a clinical environment, OCT has revolutionized the clinical practice of ophthalmology by providing 3D anatomic information. In preclinical research, OCT facilitates early stage research into pathology and drug discovery. This non-invasive technique is used to detect and monitor morphological changes of ocular tissue, in particular retinal layer thickness, which may aid in the diagnosis of certain pathological conditions such as glaucoma, age-related macular degeneration (AMD) or diabetic retinopathy. In this Sciecne Lab topic you can find basic information about OCT, articles with application examples, case studies, and links to selected publications.

Related Articles

Read our latest articles about Optical Coherence Tomography

The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments.

More Articles

RPE65 Gene Therapy Subretinal Injection: Benefits of Intraoperative OCT

Discover how RPE65 gene therapy subretinal injection procedures in patients with Leber congenital amaurosis is supported by intraoperative Optical Coherence Tomography.
Applying dispersive viscoelastic to coat the anterior chamber. Image courtesy of Arsham Sheybani, MD, Washington University School of Medicine.

Dislocated Cataract Angle Closure Aided by Intraoperative OCT

Learn how a dislocated cataract was treated with angle closure assisted by intraoperative OCT to achieve long-term good results without future lens dislocation.
Dr. Sheybani places the new subconjunctival stent in the anterior chamber. Images courtesy of Arsham Sheybani, MD.

Glaucoma Stent Revision Surgery Guided by Intraoperative OCT

Learn about a glaucoma subconjunctival stent revision guided by intraoperative OCT and the important role it plays to ensure the best outcome.
Prof. Nikolaos Bechrakis uses the Proveo 8 ceiling mounted microscope with EnFocus intraoperative OCT. Images provided by Prof. Nikolaos Bechrakis.

Posterior Segment Surgery: Benefits of Utilizing Intraoperative OCT

Learn about the value of intraoperative optical coherence tomography in posterior segment surgery to precisely locate, evaluate and manage pathologies.
Keratoplasty of pathologic cornea

Intraoperative OCT-Assisted Corneal Transplant Procedures

Learn about the use of intraoperative optical coherence tomography in corneal transplantation and how it facilitates the adaptation of the donor cornea.
Dr. Ozana Moraru shares two primary open-angle glaucoma cases in which trabeculectomy bleb needling was performed using the Leica M844 microscope with EnFocus intraoperative OCT. Image courtesy of Dr. Ozana Moraru.

How Intraoperative OCT Helps Gain Greater Insight in Glaucoma Surgery

Learn about the use of intraoperative Optical Coherence Tomography in glaucoma surgery and how it helps see subsurface tissue details.
Intraoperative OCT-assisted complex cataract surgery. Image courtesy of Dr. Ozana Moraru.

Ophthalmology: Visualization in Complex Cataract Surgery

Learn about the use of intraoperative Optical Coherence Tomography in cataract surgery and how it supports both standard and complex cataract surgery cases.
Fundus photo depicting epiretinal membrane with lamellar macular hole. Image courtesy of Robert A. Sisk, MD, FACS, Cincinnati Eye Institute.

Improve Macular Hole Surgery with Optical Coherence Tomography

A case study on the use of intraoperative OCT during macular hole surgery for pediatric lamellar macular hole repair and how it provides valuable real-time information.
Corneal transplantation. Image courtesy of Mr. David Anderson.

Ophthalmology Case Study: Corneal Transplantation

Learn about the use of intraoperative Optical Coherence Tomography in Corneal Transplantation and how it helps achieve correct positioning of donor tissue.
The intraoperative OCT showed the ellipsoid had separated from the inner retina with focal attachment to the retinal pigment epithelium (RPE). Images provided by Mr. Robert Henderson

Utility of Intraoperative OCT in Sub-Retinal Gene Therapy

Discover a case study on the use of intraoperative OCT for pediatric gene therapy and how it supports bleb placement and verifying the foveal contour.
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