Dissection Perfection
Collect pure starting material and retain spatial information for your downstream spatial biology analysis with Leica laser microdissection systems – the most flexible and powerful systems in the market.
Leica LMD6 & LMD7 Laser Microdissection Microscopes
Easily isolate regions of interest (ROI) from entire areas of tissue down to single cells, or even subcellular structures such as chromosomes, for applications such as:
- Fast and pure sample preparation for biomarker discovery
- High quality dissectates for proteomics, transcriptomics and genomics
- Convenient laser manipulation of cell cultures
We move the laser, not the sample. And we use gravity for collection. That’s why our LMD systems are the best choice for fast, perfectly cut, contamination-free, analysis-ready dissectates.
Two systems for your discoveries:
Leica LMD6 - for outstanding results in standard applications such as dissecting soft tissues e.g. brain, liver, or kidney.
Leica LMD7 - for greater flexibility with higher laser power and more laser controls, ideally suited to dissecting any kind of tissue independent of its size or shape.
LMD System with THUNDER Imaging
The LMD6 and LMD7 systems can be combined with THUNDER. The base stand of the THUNDER Imager 3D Tissue and LMD systems are the same, therefore such a combination offers:
- Lab space savings with one system for different tasks
- Laser Microdissection with the LMD without limitation
- Brilliant THUNDER fluorescence imaging using the LAS X Software Platform, even in multi-color and 3D (z-stacks) and visualization in the 3D viewer
Interface for Artificial Intelligence
Aivia is our AI-based, image visualization, analysis and interpretation platform. with the help of AI-enhanced tools such as the Pixel Classifier, Aivia can be used to automatically define Regions of interest (ROI) which are destined for Laser Microdissection (LMD). ROIs can be detected by Aivia and imported directly into the LMD software for Microdissection.
Besides Aivia other external software can be used for automatic ROI detection. The LMD software simply needs an XML file containing the ROI information.
- Mund et al., Nature Biotechnology, 2022 https://doi.org/10.1038/s41587-022-01302-5
- Mitchell at al., JoVE, 2022 https://doi.org/10.3791/64171
