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Optical Contrast Methods
Optical contrast methods give the potential to easily examine living and colorless specimens. Different microscopic techniques aim to change phase shifts caused by the interaction of light with the…
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Integrated Modulation Contrast (IMC)
Hoffman modulation contrast has established itself as a standard for the observation of unstained, low-contrast biological specimens. The integration of the modulator in the beam path of themodern…
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Fluorescence in Microscopy
Fluorescence microscopy is a special form of light microscopy. It uses the ability of fluorochromes to emit light after being excited with light of a certain wavelength. Proteins of interest can be…
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Depth of Field in Microscopy
In microscopy, depth of field is often seen as an empirical parameter. In practice it is determined by the correlation between numerical aperture, resolution and magnification. For the best possible…
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Cochlea Implants for Deaf and Severely Hard of Hearing
The cochlea implant (CI) replaces the function of the outer ear, the middle ear and the cochlea of the inner ear. Basically, it consists of an external unit comprising a microphone, speech processor,…
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New Standard in Electrophysiology and Deep Tissue Imaging
The function of nerve and muscle cells relies on ionic currents flowing through ion channels. These ion channels play a major role in cell physiology. One way to investigate ion channels is to use…
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Forensic Detection of Sperm from Sexual Assault Evidence
The impact of modern scientific methods on the analysis of crime scene evidence has dramatically changed many forensic sub-specialties. Arguably one of the most dramatic examples is the impact of…
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Quality as Clear as Glass - Polarizing Microscopy in Glass Production
An exquisite beverage deserves a high-quality glass. Even the ancient Romans made artistically crafted drinking glasses. In the Middle Ages, Venetian glassmakers were famous for the purity of their…
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The History of Stereo Microscopy
This article gives an overview on the history of stereo microscopes. The development and evolution from handcrafted instruments (late 16th to mid-18th century) to mass produced ones the last 150…
