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Science Lab
Science Lab
Das Wissensportal von Leica Microsystems bietet Ihnen Wissens- und Lehrmaterial zu den Themen der Mikroskopie. Die Inhalte sind so konzipiert, dass sie Einsteiger, erfahrene Praktiker und Wissenschaftler gleichermaßen bei ihrem alltäglichen Vorgehen und Experimenten unterstützen. Entdecken Sie interaktive Tutorials und Anwendungsberichte, erfahren Sie mehr über die Grundlagen der Mikroskopie und High-End-Technologien - werden Sie Teil der Science Lab Community und teilen Sie Ihr Wissen!
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![Image of murine dopaminergic neurons which have been marked for laser microdissection (LMD). Image of murine dopaminergic neurons which have been marked for laser microdissection (LMD).](/fileadmin/_processed_/b/f/csm_Murine_dopaminergic_neurons_marked_for_LMD_cdc0cd9eda.jpg)
Neuron Isolation in Spatial Context with Laser Microdissection (LMD)
After Alzheimer’s disease, Parkinson’s is the second most common progressive neurodegenerative disease. Before the first symptoms manifest, up to 70% of dopamine-releasing neurons in the mid-brain…
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How did Laser Microdissection enable Pioneering Neuroscience Research?
Dr. Marta Paterlini, a Senior Scientist at the Karolinska Institute, shares her experience of using laser microdissection (LMD) in groundbreaking research into adult human neurogenesis and offers…
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![How the M822 microscope enhances surgical precision in eye surgeries - Insights from Dr. Dhami. Image courtesy of Dr. Abhinav Dhami. How the M822 microscope enhances surgical precision in eye surgeries - Insights from Dr. Dhami. Image courtesy of Dr. Abhinav Dhami.](/fileadmin/_processed_/d/3/csm_Dr_Abhinav_Dhami_with_M822_28434efe21.jpg)
Buying an Ophthalmic Microscope? Gain Peers Insights from Dr. Dhami
In this article, learn how Dr. Abhinav Dhami, an ophthalmic surgery consultant in North India, enhances his surgical precision using the M822 ophthalmic microscope from Leica Microsystems and the key…
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![Region of a patterned wafer inspected using optical microscopy and automated and reproducible DIC (differential interference contrast). With DIC users are able to visualize small height differences on the wafer surface more easily. Region of a patterned wafer inspected using optical microscopy and automated and reproducible DIC (differential interference contrast). With DIC users are able to visualize small height differences on the wafer surface more easily.](/fileadmin/_processed_/6/b/csm_Patterned_wafer_inspected_by_automated_and_reproducible_DIC_11e12b5cc8.jpg)
6-Inch Wafer Inspection Microscope for Reliably Observing Small Height Differences
A 6-inch wafer inspection microscope with automated and reproducible DIC (differential interference contrast) imaging, no matter the skill level of users, is described in this article. Manufacturing…
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![Optical microscope image, which is a composition of both brightfield and fluorescence illumination, showing organic contamination on a wafer surface. Optical microscope image, which is a composition of both brightfield and fluorescence illumination, showing organic contamination on a wafer surface. The inset images in the upper left corner show the brightfield image (above) and fluorescence image (below with dark background).](/fileadmin/_processed_/a/1/csm_Organic_contamination_on_a_wafer_surface_b508d90183.jpg)
Visualizing Photoresist Residue and Organic Contamination on Wafers
As the scale of integrated circuits (ICs) on semiconductors passes below 10 nm, efficient detection of organic contamination, like photoresist residue, and defects during wafer inspection is becoming…
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![Evolved ARveo 8: Operating Room (OR) set-up. Evolved ARveo 8: Operating Room (OR) set-up.](/fileadmin/_processed_/6/3/csm_Evolved_ARveo_OR_MyVeo_Operating_Room_set-up_01_82b63ee6fb.jpg)
Augmented Reality: Transforming Neurosurgical Procedures
In this ebook, you will explore the exciting advances that Augmented Reality (AR) brings to the field of neurosurgery. This comprehensive guide, including explanatory videos, addresses key questions…
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![Multiplexed Cell DIVE imaging to characterize the tumor immune microenvironment in human colon adenocarcinoma (CAC) tissue.](/fileadmin/_processed_/4/a/csm_Human_colon_adenocarcinoma_CAC_tissue_b6afb685f3.jpg)
AI-Powered Multiplexed Image Analysis to Explore Colon Adenocarcinoma
In this application note, we demonstrate a spatial biology workflow via an AI-powered multiplexed image analysis-based exploration of the tumor immune microenvironment in colon adenocarcinoma.
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Laser Microdissection Protocols for Tissue and Cell Isolation - Download free eBook
In this Bio-protocol Selections, we present a collection of open-access, detailed methods papers using LCM to purify and isolate tissues and cells from plants, mouse embryos, cancer cells, neurons,…
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![The role of extracellular signalling mechanisms in the correct development of the human brain The role of extracellular signalling mechanisms in the correct development of the human brain](/fileadmin/_processed_/a/e/csm_The_role_of_extracellular_signalling_mechanisms_in_the_correct_development_of_the_human_brain_24ae92408c.jpg)
How do Cells Talk to Each Other During Neurodevelopment?
Professor Silvia Capello presents her group’s research on cellular crosstalk in neurodevelopmental disorders, using models such as cerebral organoids and assembloids.