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Science Lab
Science Lab
Das Wissensportal von Leica Microsystems bietet Ihnen Wissens- und Lehrmaterial zu den Themen der Mikroskopie. Die Inhalte sind so konzipiert, dass sie Einsteiger, erfahrene Praktiker und Wissenschaftler gleichermaßen bei ihrem alltäglichen Vorgehen und Experimenten unterstützen. Entdecken Sie interaktive Tutorials und Anwendungsberichte, erfahren Sie mehr über die Grundlagen der Mikroskopie und High-End-Technologien - werden Sie Teil der Science Lab Community und teilen Sie Ihr Wissen!
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![Projection of a confocal z-stack. Sum159 cells, human breast cancer cells Projection of a confocal z-stack. Sum159 cells, human breast cancer cells kindly provided by Ievgeniia Zagoriy, Mahamid Group, EMBL Heidelberg, Germany. Blue–Hoechst - indicates nuclei, Green–MitoTracker mitochondria, and red–Bodipy - lipid droplets](/fileadmin/_processed_/6/6/csm_Keyvisual-Cancer-cell-under-Cryo_Coral-Cryo_TechNote_99f1c3cd0c.jpg)
New Imaging Tools for Cryo-Light Microscopy
New cryo-light microscopy techniques like LIGHTNING and TauSense fluorescence lifetime-based tools reveal structures for cryo-electron microscopy.
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![Correlation of markers in the LM and the FIB image. Correlation of markers in the LM and the FIB image.](/fileadmin/_processed_/7/f/csm_Correlation_of_markers_in_the_LM_and_the_FIB_image_teaser_33ce8a2e69.jpg)
How to Target Fluorescent Structures in 3D for Cryo-FIB Milling
This article describes the major steps of the cryo-electron tomography workflow including super-resolution cryo-confocal microscopy. We describe how subcellular structures can be precisely located in…
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![HeLa cells. Cells kindly provided by I. Zagoriy, Mahamid Group, EMBL Heidelberg HeLa cells labeled with dark blue – Hoechst, Nuclei; magenta – MitoTracker Green, Mitochondria; turquoise - Bodipy, lipid droplets. Cells kindly provided by Ievgeniia Zagoriy, Mahamid Group, EMBL Heidelberg, Germany.](/fileadmin/_processed_/c/6/csm_LNG-non-LNGHeLa-cells_18524c7b12.jpg)
Precise 3D Targeting for EM Imaging - Access What Matters
Find out how the seamless cryo-electron tomography workflow Coral Cryo uses confocal super resolution to target your structure of interest more precisely.