![Science Lab](/fileadmin/_processed_/6/0/csm_lms-sl-header_d2c38d8093.jpg)
Science Lab
Science Lab
Das Wissensportal von Leica Microsystems bietet Ihnen Wissens- und Lehrmaterial zu den Themen der Mikroskopie. Die Inhalte sind so konzipiert, dass sie Einsteiger, erfahrene Praktiker und Wissenschaftler gleichermaßen bei ihrem alltäglichen Vorgehen und Experimenten unterstützen. Entdecken Sie interaktive Tutorials und Anwendungsberichte, erfahren Sie mehr über die Grundlagen der Mikroskopie und High-End-Technologien - werden Sie Teil der Science Lab Community und teilen Sie Ihr Wissen!
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![Image of confluent cells taken with phase contrast (left) and analyzed for confluency using AI (right). Image of confluent cells taken with phase contrast (left) and analyzed for confluency using AI (right).](/fileadmin/_processed_/3/6/csm_Confluent_cells_with_phase_contrast_and_analyzed_for_confluency_using_AI_7c617d0a36.jpg)
AI Confluency Analysis for Enhanced Precision in 2D Cell Culture
This article explains how efficient, precise confluency assessment of 2D cell culture can be done with artificial intelligence (AI). Assessing confluency, the percentage of surface area covered,…
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![AI-based cell counting performed with a phase-contrast and fluorescence image using the Mateo FL microscope. AI-based cell counting performed with a phase-contrast and fluorescence image using the Mateo FL microscope.](/fileadmin/_processed_/d/9/csm_AI-based_cell_counting_performed_with_phase-contrast_and_fluorescence_image_8227fd39a2.jpg)
Precision and Efficiency with AI-Enhanced Cell Counting
This article describes the use of artificial intelligence (AI) for precise and efficient cell counting. Accurate cell counting is important for research with 2D cell cultures, e.g., cellular dynamics,…
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![AI-based transfection analysis (left) of U2OS cells which were transfected with a fluorescently labelled protein. A fluorescence image of the cells (right) is also shown. The analysis and imaging were performed with Mateo FL. AI-based transfection analysis (left) of U2OS cells which were transfected with a fluorescently labelled protein. A fluorescence image of the cells (right) is also shown. The analysis and imaging were performed with Mateo FL.](/fileadmin/_processed_/4/c/csm_AI-based_analysis_of_U2OS_cells_transfected_with_fluorescently_labelled_protein_65d00c857b.jpg)
Leveraging AI for Efficient Analysis of Cell Transfection
This article explores the pivotal role of artificial intelligence (AI) in optimizing transfection efficiency measurements within the context of 2D cell culture studies. Precise and reliable…
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![Multiplexed Cell DIVE imaging to characterize the tumor immune microenvironment in human colon adenocarcinoma (CAC) tissue.](/fileadmin/_processed_/4/a/csm_Human_colon_adenocarcinoma_CAC_tissue_b6afb685f3.jpg)
AI-Powered Multiplexed Image Analysis to Explore Colon Adenocarcinoma
In this application note, we demonstrate a spatial biology workflow via an AI-powered multiplexed image analysis-based exploration of the tumor immune microenvironment in colon adenocarcinoma.
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![Multiplexed Cell DIVE imaging of selected clusters and unique cell populations identified in mucinous cystadenocarcinoma of the ovary.](/fileadmin/_processed_/8/6/csm_Cell_populations_identified_in_mucinous_cystadenocarcinoma_of_ovary_d43ca4a170.jpg)
A Meta-cancer Analysis of the Tumor Spatial Microenvironment
Learn how clustering analysis of Cell DIVE datasets in Aivia can be used to understand tissue-specific and pan-cancer mechanisms of cancer progression
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![Multiplexed Cell DIVE imaging of Colon Adenocarcinoma (CAC) tissue. Multiplexed Cell DIVE imaging of Colon Adenocarcinoma (CAC) tissue. A panel of approximately 30 biomarkers targeted towards various leukocyte lineages, epithelial, stromal, and endothelial cell types was utilized to characterize the tumor immune microenvironment in human colon adenocarcinoma (CAC) tissue.](/fileadmin/_processed_/c/7/csm_Colon_Adenocarcinoma_CAC_tissue_multiplexed_Cell_DIVE_image_427e3f34d4.jpg)
Mapping the Landscape of Colorectal Adenocarcinoma with Imaging and AI
Discover deep insights in colon adenocarcinoma and other immuno-oncology realms through the potent combination of multiplexed imaging of Cell DIVE and Aivia AI-based image analysis
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![Clustering based analysis reveals various immune cell populations enriched in tumor cells within CT26.WT syngeneic mouse tumor models. Clustering based analysis reveals various immune cell populations enriched in tumor cells within CT26.WT syngeneic mouse tumor models.](/fileadmin/_processed_/f/e/csm_Immune_cells_in_tumor_cells_within_CT26WT_syngeneic_mouse_tumor_models_7de627c156.jpg)
Spatial Architecture of Tumor and Immune Cells in Tumor Tissues
Dig deep into the spatial biology of cancer progression and mouse immune-oncology in this poster, and learn how tumor metabolism can effect immune cell function.
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![Mouse whole-mount retina. Image courtesy of the Experimental Ophthalmology Group, University of Murcia, Spain. Mouse whole-mount retina. Image courtesy of the Experimental Ophthalmology Group, University of Murcia, Spain.](/fileadmin/_processed_/4/a/csm_Mouse_whole-mount_retina_Thundered_abe5e38481.jpg)
Fast, High Acuity Imaging and AI-assisted Analysis
The use of state-of-the-art AI systems is pushing image analysis into a new generation. Challenges like the conflict between imaging power and sample integrity are being overcome with THUNDER’s…
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![3D reconstruction of an isolated human islet 3D reconstruction of an isolated human islet](/fileadmin/_processed_/d/1/csm_THUNDER-Imager-3D-Cell-Culture_isolated-human-islet_6bcb590f44.jpg)
Create New Options for Live Cell Imaging
The use of state-of-the-art AI systems is pushing image analysis into a new generation. Challenges like the conflict between imaging power and sample integrity are being overcome with THUNDER’s…