![Science Lab](/fileadmin/_processed_/6/0/csm_lms-sl-header_d2c38d8093.jpg)
Science Lab
Science Lab
Das Wissensportal von Leica Microsystems bietet Ihnen Wissens- und Lehrmaterial zu den Themen der Mikroskopie. Die Inhalte sind so konzipiert, dass sie Einsteiger, erfahrene Praktiker und Wissenschaftler gleichermaßen bei ihrem alltäglichen Vorgehen und Experimenten unterstützen. Entdecken Sie interaktive Tutorials und Anwendungsberichte, erfahren Sie mehr über die Grundlagen der Mikroskopie und High-End-Technologien - werden Sie Teil der Science Lab Community und teilen Sie Ihr Wissen!
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![[Translate to German:] Multi-tissue array with 4 markers shown including DAPI, NaKATPase, PanCk, and Vimentin. [Translate to German:] Multi-tissue array with 4 markers shown including DAPI, NaKATPase, PanCk, and Vimentin.](/fileadmin/_processed_/8/b/csm_Multi-tissue_array_with_4_markers_93819abf05.jpg)
Räumliche Biologie: Erwägung neuer Wege
Räumliche Biologie: Forschung zu Anordnung und Interaktion von Molekülen, Zellen und Geweben in ihrem nativen räumlichen Kontext
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![Branched organoid growing in collagen where the Nuclei are labeled blue. To detect the mechanosignaling process, the YAP1 is labeled green. Branched organoid growing in collagen where the Nuclei are labeled blue. To detect the mechanosignaling process, the YAP1 is labeled green.](/fileadmin/_processed_/a/e/csm_Branched_organoid_growing_in_collagen_083254eb44.jpg)
Examining Developmental Processes In Cancer Organoids
Interview: Prof. Bausch and Dr. Pastucha, Technical University of Munich, discuss using microscopy to study development of organoids, stem cells, and other relevant disease models for biomedical…
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![[Translate to German:] Cell counts for each biomarker were divided by total number of cells to give a percentage of biomarker positive cells out of total cells for each biomarker. [Translate to German:] Cell counts for each biomarker were divided by total number of cells to give a percentage of biomarker positive cells out of total cells for each biomarker.](/fileadmin/_processed_/5/3/csm_Cell_counts_for_biomarkers_with_Cell_DIVE_ee648b397a.jpg)
Methoden zur Verbesserung der Reproduzierbarkeit in der räumlichen Biologieforschung
Durch den Einsatz von Automatisierung, hochwertigen Antikörpern und einem bewährten Multiplex-Imaging-Workflow ist Cell DIVE in der Lage, reproduzierbare Ergebnisse zu liefern. In diesem Poster…
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![PDAC Multiplexed imaging of CST panels enables an examination of immune cell components in pancreatic ductal adenocarcinoma (IPDAC) tissue on a single slide. PDAC Multiplexed imaging of CST panels enables an examination of immune cell components in pancreatic ductal adenocarcinoma (IPDAC) tissue on a single slide.](/fileadmin/_processed_/a/d/csm_Pancreatic_ductal_adenocarcinoma_tissue_3d61c18a2d.jpg)
Characterizing tumor environment to reveal insights and spatial resolution
Antibodies from Cell Signaling Technology are validated for use with the Cell DIVE multiplexing workflow and used to probe cell lineages in the tumor microenvironment
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![Krebszellen Krebszellen](/fileadmin/_processed_/6/b/csm_Cancer_cells_0188d06359.jpg)
Die Rolle des Eisenstoffwechsels bei der Krebsentwicklung
Der Eisenstoffwechsel spielt eine Rolle bei der Entstehung und dem Fortschreiten von Krebs und beeinflusst die Immunreaktion. Zu verstehen, wie Eisen Krebs und das Immunsystem beeinflusst, kann die…
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![Pancreatic Ductal Adenocarcinoma with 5 biomarkers shown – SMA, PanCK PCK26, PanCK AE1, Vimentin, and Glut1. Pancreatic Ductal Adenocarcinoma with 5 biomarkers shown – SMA, PanCK PCK26, PanCK AE1, Vimentin, and Glut1.](/fileadmin/_processed_/3/a/csm_Pancreatic_Ductal_Adenocarcinoma_with_5_biomarkers_7ea537ecff.jpg)
Dig Deeper Into the Complexities of Pancreatic Cancer with Multiplex Imaging
Cell DIVE is an iterative staining workflow for multiplexed imaging that unveils biological pathways to dig deeper into the complexities of pancreatic cancer.
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![Pancreatic ductal adenocarcinoma tissue section imaged with Cell DIVE Pancreatic ductal adenocarcinoma tissue section imaged with Cell DIVE](/fileadmin/_processed_/f/8/csm_Pancreatic_ductal_adenocarcinoma_tissue_section_teaser_eae5765765.jpg)
Multiplexed Imaging Types, Benefits and Applications
Multiplexed imaging is an emerging and exciting way to extract information from human tissue samples by visualizing many more biomarkers than traditional microscopy. By observing many biomarkers…
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![H&E stained micrograph of an intramucosal esophageal adenocarcinoma (left) enhanced with Aivia’s Pixel Classifier (right) H&E stained micrograph of an intramucosal esophageal adenocarcinoma (left) enhanced with Aivia’s Pixel Classifier (right)](/fileadmin/_processed_/5/4/csm_Aivia_Image_Analysis_Workshop_-_Cancer_e2259a2aee.png)
Simplifying the Cancer Biology Image Analysis Workflow
As cancer biology data sets grow, so do the challenges in microscopy image analysis. Aivia experts cover how to overcome these challenges with AI.
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![3D-volume-rendered light-sheet microscope image of a spheroid showing depth coding in different colors. 3D-volume-rendered light-sheet microscope image of a spheroid showing depth coding in different colors.](/fileadmin/_processed_/4/8/csm_Spheroid_showing_depth_coding_in_different_colors_3D_DLS_2cc9dea009.jpg)
Imaging of Anti-Cancer Drug Uptake in Spheroids using DLS
Spheroid 3D cell culture models mimic the physiology and functions of living tissues making them a useful tool to study tumor morphology and screen anti-cancer drugs. The drug AZD2014 is a recognized…