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Kryo-Elektronen-Tomographie
Mit der Kryo-Elektronentomographie (CryoET) lassen sich Biomoleküle in ihrer zellulären Umgebung mit einer noch nie dagewesenen Auflösung von weniger als einem Nanometer auflösen.
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Streamline your EM Sample Preparation Workflow for Biological Applications
Master EM sample preparation, including ultramicrotomy, for life sciences in this expert eBook!
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New Imaging Tools for Cryo-Light Microscopy
New cryo-light microscopy techniques like LIGHTNING and TauSense fluorescence lifetime-based tools reveal structures for cryo-electron microscopy.
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How to Target Fluorescent Structures in 3D for Cryo-FIB Milling
This article describes the major steps of the cryo-electron tomography workflow including super-resolution cryo-confocal microscopy. We describe how subcellular structures can be precisely located in…
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Precise 3D Targeting for EM Imaging - Access What Matters
Find out how the seamless cryo-electron tomography workflow Coral Cryo uses confocal super resolution to target your structure of interest more precisely.
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How to Successfully Perform Live-cell CLEM
The Leica Nano workflow provides a streamlined live-cell CLEM solution for getting insight bout structural changes of cellular components over time. Besides the technical handling described in the…
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How to Successfully Implement Coral Life
The live-cell CLEM workflow allows you to capture dynamic information related to a relevant biological process as it happens and put these observations into their ultrastructural context. The Leica…
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Advancing Cellular Ultrastructure Research
Freeze-fracture and freeze-etching are useful tools for studying flexible membrane-associated structures such as tight junctions or the enteric glycocalyx. Freeze-fracture and etching are two…
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The Cryo-CLEM Journey
This article describes the Cryo-CLEM technology and the benefits it can provide for scientists. Additionally, some scientific publications are highlighted.
Recent developments in cryo electron…
