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Science Lab

Science Lab

Das Wissensportal von Leica Microsystems bietet Ihnen Wissens- und Lehrmaterial zu den Themen der Mikroskopie. Die Inhalte sind so konzipiert, dass sie Einsteiger, erfahrene Praktiker und Wissenschaftler gleichermaßen bei ihrem alltäglichen Vorgehen und Experimenten unterstützen. Entdecken Sie interaktive Tutorials und Anwendungsberichte, erfahren Sie mehr über die Grundlagen der Mikroskopie und High-End-Technologien - werden Sie Teil der Science Lab Community und teilen Sie Ihr Wissen!
U2OS cells stained with Hoechst for nuclei (blue), MitoTracker green (Mitochondria structure, green) and TMRE (active mitochondria, magenta) and SiR for tubulin (red). Simultaneous acquisition of four channel large area overview using Spiral scan feature using the 10x/1.20 CS2 Water MotCORR objective.

How To Get Multi Label Experiment Data With Full Spatiotemporal Correlation

This video on demand focuses on the special challenges of live cell experiments. Our hosts Lynne Turnbull and Oliver Schlicker use the example of studying the mitochondrial activity of live cells.…
Multi-color SRS image of a tri-cellular cancer spheroid

The Potential of Coherent Raman Scattering Microscopy at a Glance

Coherent Raman scattering microscopy (CRS) is a powerful approach for label-free, chemically specific imaging. It is based on the characteristic intrinsic vibrational contrast of molecules in the…

A Versatile Palette of Fluorescent Probes

Researchers at the Max Planck Institute for Medical Research in Heidelberg have developed a general strategy to synthesize live-cell compatible fluorogenic probes, and the result are the new MaP (Max…
Dual color volume rendering of Drp1 oligomers (green) and mito OM (red) in a live U2OS cell

Multicolor 4D Super Resolution Light Sheet Microscopy

The AI Microscopy Symposium offers a unique forum for discussing the latest AI-based technologies and tools in the field of microscopy and biomedical imaging. In this scientific presentation, Yuxuan…
Zelluläres Mikrotubuli-Netzwerk in einer Fibroblastenzelle.

Wie Sie Gewebeproben für die Immunfluoreszenz-Mikroskopie vorbereiten

Immunfluoreszenz (IF) ist eine leistungsfähige Methode zur Visualisierung intrazellulärer Prozesse, Bedingungen und Strukturen. IF-Präparate können mit verschiedenen Mikroskopietechniken (z. B. CLSM,…

Live-Cell Imaging Techniques

The understanding of complex and/or fast cellular dynamics is an important step for exploring biological processes. Therefore, today’s life science research is increasingly focused on dynamic…
Single timepoint of a drosophilia embryo, 3D object detection

Examining Critical Developmental Events in High-Definition

Extended live cell imaging of embryo development requires a delicate balance between light exposure, temporal resolution and spatial resolution to maintain cells’ viability. Compromises between the…
3D-volume-rendered light-sheet microscope image of a spheroid showing depth coding in different colors.

Imaging of Anti-Cancer Drug Uptake in Spheroids using DLS

Spheroid 3D cell culture models mimic the physiology and functions of living tissues making them a useful tool to study tumor morphology and screen anti-cancer drugs. The drug AZD2014 is a recognized…
Spontaneous colon adenoma

Intravital Microscopy of Cancer

Join our guest speaker Prof Dr Jacco van Rheenen, as he presents his work on the identity, behavior and fate of cells that drive the initiation and progression of cancer.
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