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Science Lab
Science Lab
Das Wissensportal von Leica Microsystems bietet Ihnen Wissens- und Lehrmaterial zu den Themen der Mikroskopie. Die Inhalte sind so konzipiert, dass sie Einsteiger, erfahrene Praktiker und Wissenschaftler gleichermaßen bei ihrem alltäglichen Vorgehen und Experimenten unterstützen. Entdecken Sie interaktive Tutorials und Anwendungsberichte, erfahren Sie mehr über die Grundlagen der Mikroskopie und High-End-Technologien - werden Sie Teil der Science Lab Community und teilen Sie Ihr Wissen!
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![3D reconstruction of an isolated human islet 3D reconstruction of an isolated human islet](/fileadmin/_processed_/d/1/csm_THUNDER-Imager-3D-Cell-Culture_isolated-human-islet_6bcb590f44.jpg)
Create New Options for Live Cell Imaging
The use of state-of-the-art AI systems is pushing image analysis into a new generation. Challenges like the conflict between imaging power and sample integrity are being overcome with THUNDER’s…
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![Raw widefield and THUNDER image of a mouse dorsal root ganglion with tdTomato (red) expressed in the sensory neurons. Raw widefield and THUNDER image of a mouse dorsal root ganglion with tdTomato (red) expressed in the sensory neurons.](/fileadmin/_processed_/4/3/csm_Mouse_dorsal_root_ganglion_sensory_neurons_THUNDER_teaser_86235c43e7.jpg)
Fast, High-contrast 3D Imaging of Sensory Neurons
This article discusses how fast, high-contrast 3D imaging of dorsal root ganglion (DRG) tissue with a THUNDER Imager Tissue using large volume computational clearing (LVCC) allows sensory neurons to…
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![Identification of distinct structures_roundworm_Ascaris_female Identification of distinct structures_roundworm_Ascaris_female](/fileadmin/_processed_/a/b/csm_Identification_of_distinct_structures_roundworm_Ascaris_female_e4b7a4d72d.jpg)
Find Relevant Specimen Details from Overviews
Switch from searching image by image to seeing the full overview of samples quickly and identifying the important specimen details instantly with confocal microscopy. Use that knowledge to set up…
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![Blood vessels imaged with THUNDER & Aivia Left-hand image: The distribution of immune cells (white) and blood vessels (pink) in white adipose tissue (image captured using the THUNDER Imager 3D Cell Culture). Right-hand image: The same image after automated analysis using Aivia, with each immune cell color-coded based on its distance to the nearest blood vessel. Image courtesy of Dr. Selina Keppler, Munich, Germany.](/fileadmin/_processed_/f/a/csm_Fat_tissue_THUNDER_THUNDER-Aivia_teaser_e142629a8c.jpg)
Accurately Analyze Fluorescent Widefield Images
The specificity of fluorescence microscopy allows researchers to accurately observe and analyze biological processes and structures quickly and easily, even when using thick or large samples. However,…
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![](/fileadmin/_processed_/a/d/csm_thunder-and-aivia-teaser_e1a10860b2.jpg)
Save Time and Effort with AI-assisted Fluorescence Image Analysis
The powerful synergy of THUNDER and Aivia analyze fluorescence images with greater accuracy, even when using low light excitation.
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![Fluorescently stained mouse tibia, imaged with a THUNDER Imager 3D Tissue. Courtesy of Dr. Anjali Kusumbe, University of Oxford, UK.](/fileadmin/academy/2021/Abstracts_Interviews_Webinars/High-resolution_3D_imaging_to_investigate_tissue_ageing_teaser.jpg)
High-resolution 3D Imaging to Investigate Tissue Ageing
Award-winning researcher Dr. Anjali Kusumbe demonstrates age-related changes in vascular microenvironments through single-cell resolution 3D imaging of young and aged organs.
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![HeLa Kyoto cells HeLa Kyoto cells (HKF1, H2B-mCherry, alpha Tubulin, mEGFP). Left image: Maximum projection of a z-stack prior to ICC and LVCC. Right image: Maximum projection of a mosaic z-stack after ICC and LVCC.](/fileadmin/_processed_/6/a/csm_How_to_improve_live_cell_imaging_with_Leica_Nano_Workflow_teaser_04b9da73e4.jpg)
How to Improve Live Cell Imaging with Coral Life
For live-cell CLEM applications, light microscopy imaging is a critical step for identifying the right cell in the right state at the right time. In this article, Leica experts share their insights on…
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![](/fileadmin/academy/2021/Abstracts_Interviews_Webinars/Optimizing_THUNDER_platform_for_high-content_slide_scanning_teaser.jpg)
Optimizing THUNDER Platform for High-Content Slide Scanning
With rising demand for full-tissue imaging and the need for FL signal quantitation in diverse biological specimens, the limits on HC imaging technology are tested, while user trainability and…
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![C. elegans Gonades C. elegans Gonades - THUNDER Imager Adult hermaphrodit, Staining: blue - DAPI (Nucleus), green - SP56 (sperms), red - RME-2 (oocyte), mangenta - PGL-1 (RNA + protein granules) Image courtesy of Prof. Dr. Christian Eckmann, Martin Luther University, Halle, Germany](/fileadmin/academy/2019/Image_Gallery__THUNDER_Imager/THUNDER-Imager_C-elegans_Gonades_Physiology_3600.jpg)
Physiology Image Gallery
Physiology is about the processes and functions within a living organism. Research in physiology focuses on the activities and functions of an organism’s organs, tissues, or cells, including the…