Leica Microsystems: Science Lab

Science Lab

Das Wissensportal von Leica Microsystems bietet Ihnen Wissens- und Lehrmaterial zu den Themen der Mikroskopie. Die Inhalte sind so konzipiert, dass sie Einsteiger, erfahrene Praktiker und Wissenschaftler gleichermaßen bei ihrem alltäglichen Vorgehen und Experimenten unterstützen. Entdecken Sie interaktive Tutorials und Anwendungsberichte, erfahren Sie mehr über die Grundlagen der Mikroskopie und High-End-Technologien - werden Sie Teil der Science Lab Community und teilen Sie Ihr Wissen!

Fundus photo depicting epiretinal membrane with lamellar macular hole. Image courtesy of Robert A. Sisk, MD, FACS, Cincinnati Eye Institute.

Improve Macular Hole Surgery with Optical Coherence Tomography

A case study on the use of intraoperative OCT during macular hole surgery for pediatric lamellar macular hole repair and how it provides valuable real-time information.

Augmented Reality fluorescence supports each step of neurovascular surgery procedures. Image courtesy of Dr. Christof Renner.

Use of AR Fluorescence in Neurovascular Surgery

Learn about the use of GLOW800 Augmented Reality in neurovascular surgery through clinical cases and videos, including aneurysm and tumor resection cases.

Corneal transplantation. Image courtesy of Mr. David Anderson.

Ophthalmology Case Study: Corneal Transplantation

Learn about the use of intraoperative Optical Coherence Tomography in Corneal Transplantation and how it helps achieve correct positioning of donor tissue.

Cell counts for each biomarker were divided by total number of cells to give a percentage of biomarker positive cells out of total cells for each biomarker.

Methoden zur Verbesserung der Reproduzierbarkeit in der räumlichen Biologieforschung

Durch den Einsatz von Automatisierung, hochwertigen Antikörpern und einem bewährten Multiplex-Imaging-Workflow ist Cell DIVE in der Lage, reproduzierbare Ergebnisse zu liefern. In diesem Poster…

PDAC Multiplexed imaging of CST panels enables an examination of immune cell components in pancreatic ductal adenocarcinoma (IPDAC) tissue on a single slide.

Characterizing tumor environment to reveal insights and spatial resolution

Antibodies from Cell Signaling Technology are validated for use with the Cell DIVE multiplexing workflow and used to probe cell lineages in the tumor microenvironment

The intraoperative OCT showed the ellipsoid had separated from the inner retina with focal attachment to the retinal pigment epithelium (RPE). Images provided by Mr. Robert Henderson

Utility of Intraoperative OCT in Sub-Retinal Gene Therapy

Discover a case study on the use of intraoperative OCT for pediatric gene therapy and how it supports bleb placement and verifying the foveal contour.

Raw widefield and THUNDER image of calcium transients in Drosophila embryos. Courtesy A. Carreira-Rosario, Clandinin laboratory, California, USA.

Central Nervous System (CNS) Development and Activity in Organisms

This article shows how studying central nervous system (CNS) development in Drosophila-melanogaster embryos expressing a GCaMP calcium indicator in the neurons can be improved with a THUNDER Imager.

Diffuse retinal degeneration with relative macular sparing.

Ophthalmic Gene Therapy Subretinal Injection

Case study on the use of intraoperative OCT for Leber congenital amaurosis macular repair and ophthalmic gene therapy subretinal injection.

Raw widefield and THUNDER image of transversal mouse adult fiber lens section. Courtesy N. Houssin, Plagemen lab, Ohio State University, Columbus, USA.

Studying Ocular Birth Defects

This article discusses how lens formation and ocular birth defects can be studied with sharp widefield microscopy images which are acquired rapidly. The mouse ocular lens is used as a model to study…