Light Sheet Microscopes

Discover advanced light sheet microscopy solutions from Leica Microsystems. Our portfolio combines cutting-edge technology with exceptional imaging capabilities to enhance your research.

Key benefits

Experience the key benefits of imaging live specimens by capturing sharp, uniformly illuminated images of large-volume specimens over extended periods of time. Benefit from easy sample mounting, protocol maintenance, and on-the-fly experimental adjustments for flexibility and convenience. Our offerings include stand-alone solutions and integration with confocal microscopes for fast and gentle volumetric imaging.

Push the boundaries of research with reliable, precise and versatile light sheet microscopy solutions from Leica Microsystems to study developing embryos, spheroids, organoids or other delicate samples.

Intestinal organoids label with FUCCI reporter to follow cell cycle dynamics. Courtesy of Franziska Moos. Liberali lab. FMI Basel (Switzerland).

Image of C2C12 cells: The cells are stained with lamin B (magenta) which indicates nuclear structure, Hoechst (blue) indicating DNA, and γH2AX (yellow) indicating damage to DNA. Cells were imaged using a THUNDER Imager 3D Live Cell with a 63X/1.4 oil immersion objective.

Cell Biology

When your research is centered on understanding the cellular basis of human health and disease, it is critical to investigate the cells of interest in spatiotemporal and molecular detail. Consequently, microscopy is an ever-important tool in cell biology, allowing you to study your specimens in detail within their structural environment, as well as, analyze cellular organelles and macromolecules.

Organoids and 3D Cell Culture

One of the most exciting recent advancements in life science research is the development of 3D cell culture systems, such as organoids, spheroids, or organ-on-a-chip models. A 3D cell culture is an artificial environment in which cells are able to grow and interact with their surroundings in all 3 dimensions. These conditions are similar to how they would be in vivo.

Life Science Research

Leica microscopes support the imaging needs of the life science research community with advanced innovation and technical expertise for the visualization, measurement, and analysis of subcellular structures and biomolecules.

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Light Sheet Microscopes