Leica Microsystems
Leica Microsystems is a world leader in microscopes and scientific instruments. Founded as a family business in the nineteenth century, the company’s history was marked by unparalleled innovation on its way to becoming a global enterprise.
Its historically close cooperation with the scientific community is the key to Leica Microsystems’ tradition of innovation, which draws on users’ ideas and creates solutions tailored to their requirements. At the global level, Leica Microsystems is organized in three divisions, all of which are among the leaders in their respective fields: Life Science, Industry and Medical.
The company is represented in over 100 countries with 6 manufacturing facilities in 5 countries, sales and service organizations in 20 countries, and an international network of dealers. The company is headquartered in Wetzlar, Germany.
Mapping the Landscape of Colorectal Adenocarcinoma with Imaging and AI
Discover deep insights in colon adenocarcinoma and other immuno-oncology realms through the potent combination of multiplexed imaging of Cell DIVE and Aivia AI-based image analysis
Spatial Architecture of Tumor and Immune Cells in Tumor Tissues
Dig deep into the spatial biology of cancer progression and mouse immune-oncology in this poster, and learn how tumor metabolism can effect immune cell function.
IBEX, Cell DIVE, and RNA-Seq: A Multi-omics Approach to Follicular Lymphoma
In a recent study by Radtke et al., a multi-omics spatial biology approach helps shed light on early relapsing lymphoma patients
Overcoming Observational Challenges in Organoid 3D Cell Culture
Learn how to overcome challenges in observing organoid growth. Read this article and discover new solutions for real-time monitoring which do not disturb the 3D structure of the organoids over time.
Burr Detection During Battery Manufacturing
See how optical microscopy can be used for burr detection on battery electrodes and determination of damage potential to achieve rapid and reliable quality control during battery manufacturing.
Battery Particle Detection During the Production Process
How battery particle detection and analysis is enhanced with optical microscopy and laser spectroscopy for rapid, reliable, and cost-effective QC during battery production is explained in this…
Rapid Check of Live Stem Cells in Cell-Culture Inserts set in Multi-Well Plates
See how efficient imaging of live iPSC stem cells within cell-culture inserts set in a multi-well plate can be done to evaluate the cells using a THUNDER Imager. Just read this article.
Automatic Alignment of Sample and Knife for High Sectioning Quality
Automatic alignment of sample and knife on the ultramicrotome UC Enuity, enabling even untrained users to create ultrathin sections with reduced risk of losing precious sections.
High Quality Sectioning in Ultramicrotomy
Discover the significance of achieving high-quality uniform sections with ultramicrotomy for precise imaging in electron microscopy.
Extended Live-cell Imaging at Nanoscale Resolution
Extended live-cell imaging with TauSTED Xtend. Combined spatial and lifetime information allow super-resolution microscopy at extremely low light dose.
The Guide to STED Sample Preparation
This guide is intended to help users optimize sample preparation for stimulated emission depletion (STED) nanoscopy, specifically when using the STED microscope from Leica Microsystems. It gives an…
How to Streamline Your Histology Workflows
Streamline your histology workflows. The unique Fluosync detection method embedded into Mica enables high-res RGB color imaging in one shot.
How to Prepare Samples for Stimulated Raman Scattering (SRS) imaging
Find here guidelines for how to prepare samples for stimulated Raman scattering (SRS), acquire images, analyze data, and develop suitable workflows. SRS spectroscopic imaging is also known as SRS…
RPE65 Gene Therapy Subretinal Injection: Benefits of Intraoperative OCT
Discover how RPE65 gene therapy subretinal injection procedures in patients with Leber congenital amaurosis is supported by intraoperative Optical Coherence Tomography.
Accelerating Discovery for Multiplexed Imaging of Diverse Tissues
Explore IBEX: Open-source multiplexed imaging. Join the collaborative IBEX Imaging Community for optimized tissue processing, antibody selection, and human atlas construction.
Key Factors for Efficient Cleanliness Analysis
An overview of the key factors necessary for technical cleanliness and efficient cleanliness analysis concerning automotive and electronics manufacturing and production is provided in this article.
Technical Terms for Digital Microscope Cameras and Image Analysis
Learn more about the basic principles behind digital microscope camera technologies, how digital cameras work, and take advantage of a reference list of technical terms from this article.
Rapid Semiconductor Inspection with Microscope Contrast Methods
Semiconductor inspection during the production of patterned wafers and ICs (integrated circuits) is important for identifying and minimizing defects. To increase the efficiency of quality control in…
Transforming Multiplexed 2D Data into Spatial Insights Guided by AI
Aivia 13 handles large 2D images and enables researchers to obtain deep insights into microenvironment surrounding their phenotypes with millions of detected objects and automatic clustering up to 30…
Notable AI-based Solutions for Phenotypic Drug Screening
Learn about notable optical microscope solutions for phenotypic drug screening using 3D-cell culture, both planning and execution, from this free, on-demand webinar.
Understanding Tumor Heterogeneity with Protein Marker Imaging
Explore tumor heterogeneity and immune cell dynamics. See how quantitative imaging analysis reveals spatial relationships and molecular insights crucial for advancing cancer research and therapeutics.
The Shape of the Brain: Spatial Biology of Alzheimer’s Disease
Uncover cell identity and brain structure in Alzheimer's disease with Cell DIVE multiplexed imaging, demonstrating how spatial biology can lead to advances in therapy development for…
Cross-section Analysis for Electronics Manufacturing
This article describes cross-section analysis for electronics concerning quality control and failure analysis of printed circuit boards (PCBs) and assemblies (PCBAs), integrated circuits (ICs), etc.
How to Get Deeper Insights into your Organoid and Spheroid Models
In this eBook, learn about key considerations for imaging 3D cultures, such as organoids and spheroids, and discover microscopy solutions to shed new insights into dynamic processes in 3D real-time
Streamline your EM Sample Preparation Workflow for Biological Applications
Master EM sample preparation, including ultramicrotomy, for life sciences in this expert eBook!
Studying Virus Replication with Fluorescence Microscopy
The results from research on SARS-CoV-2 virus replication kinetics, adaption capabilities, and cytopathology in Vero E6 cells, done with the help of fluorescence microscopy, are described in this…
In Situ Identification of Cancer Stem Cell Niches in Hepatocellular Carcinoma
Discover how multiplexed imaging technology uncovers cancer stem cell niches in Hepatocellular Carcinoma using multiplex immunodetection, revealing extracellular matrix dynamics. Explore precise…
Understanding Clearly the Magnification of Microscopy
To help users better understand the magnification of microscopy and how to determine the useful range of magnification values for digital microscopes, this article provides helpful guidelines.
Epi-Illumination Fluorescence and Reflection-Contrast Microscopy
This article discusses the development of epi-illumination and reflection contrast for fluorescence microscopy concerning life-science applications. Much was done by the Ploem research group…
Discover how Multiplexed Bioimaging can Advance Cancer Research
Explore multiplexing with up to 60 biomarkers, enabling advanced tumor imaging approaches to gather precise, spatially-resolved single-cell data that helps enhance cancer research and clinical…
