Leica Microsystems
Leica Microsystems is a world leader in microscopes and scientific instruments. Founded as a family business in the nineteenth century, the company’s history was marked by unparalleled innovation on its way to becoming a global enterprise.
Its historically close cooperation with the scientific community is the key to Leica Microsystems’ tradition of innovation, which draws on users’ ideas and creates solutions tailored to their requirements. At the global level, Leica Microsystems is organized in three divisions, all of which are among the leaders in their respective fields: Life Science, Industry and Medical.
The company is represented in over 100 countries with 6 manufacturing facilities in 5 countries, sales and service organizations in 20 countries, and an international network of dealers. The company is headquartered in Wetzlar, Germany.
Advanced Visualization in Spine Surgery
There have been meaningful advances in spine surgery in recent years. Minimally Invasive Spine Surgery (MISS) techniques provide significant benefits, helping to minimize surgical trauma, improve…
How Augmented Reality is Transforming Vascular Neurosurgery
Augmented Reality is changing surgery, with new information helping to improve the precision and safety of procedures. This is especially true in vascular neurosurgery where Augmented Reality is…
Overcoming Ophthalmologic Surgery Challenges
Ophthalmology surgical procedures involving both the anterior and posterior segment can be particularly challenging. Good visualization is required to operate with precision and confidence.
Prof.…
Advanced Visualization in Maxillofacial Plastic and Reconstructive Surgery
Plastic and Reconstructive Surgery is very demanding. Surgical microscopes play an important role, helping to ensure flaps are well vascularized.
Dr. Christine Bach is a Plastic and Reconstructive…
Studying Cell Division
Cell division is a biological process during which all cellular components must be distributed among the daughter cells. The division process requires firm coordination for success. Microscopy is…
Investigating Synapses in Brain Slices with Enhanced Functional Electron Microscopy
A fundamental question of neuroscience is: what is the relationship between structural and functional properties of synapses? Over the last few decades, electrophysiology has shed light on synaptic…
GLOW800 Augmented Reality Fluorescence in AVM (Arteriovenous Malformation) Treatment
In this case study Prof. Dr. Feres Chaddad talks about the treatment of AVMs. It illustrates how the Augmented Reality Fluorescence GLOW800 can help surgeons during microsurgical resection by…
The Power of Pairing Adaptive Deconvolution with Computational Clearing
Learn how deconvolution allows you to overcome losses in image resolution and contrast in widefield fluorescence microscopy due to the wave nature of light and the diffraction of light by optical…
Improvement of Imaging Techniques to Understand Organelle Membrane Cell Dynamics
Understanding cell functions in normal and tumorous tissue is a key factor in advancing research of potential treatment strategies and understanding why some treatments might fail. Single-cell…
Neurovascular Surgery & Augmented Reality Fluorescence
Vascular neurosurgery is highly complex. Surgeons need to be able to rely on robust anatomical information. As such, visualization technologies play an essential role.
Prof. Nils Ole Schmidt is a…
Topographic Analysis of Firing Pin Impressions on Cartridge Cases
The analysis of fired cartridges for primer cup morphology and flattening and firing pin impression (crater) depth using topographic data is discussed in this article. Topographical analysis of the…
Studying Pulmonary Fibrosis
The results shown in this article demonstrate that fibrotic and non-fibrotic regions of collagen present in mouse lung tissue can be distinguished better with polarized light compared to brightfield.…
Advancing Cell Biology with Cryo-Correlative Microscopy
Correlative light and electron microscopy (CLEM) advances biological discoveries by merging different microscopes and imaging modalities to study systems in 4D. Combining fluorescence microscopy with…
Image Gallery: THUNDER Imager
To help you answer important scientific questions, THUNDER Imagers eliminate the out-of-focus blur that clouds the view of thick samples when using camera-based fluorescence microscopes. They achieve…
Keeping Particulate Contamination Under Control in Pharmaceutical Products
This article describes how a 2-methods-in-1 solution combining optical microscopy and laser induced breakdown spectroscopy (LIBS) can be utilized for identification of particulate contaminants in the…
Fast Visual and Chemical Analysis of Contamination and Underlying Layers
Visual and chemical analysis of contamination on materials with a 2-methods-in-1 solution leading to an efficient, more complete analysis workflow is described in this report. A 2-in-1 solution,…
Hand-Held OCT Clinical & Research Applications
Hand-held Optical Coherence Tomography (OCT) has revolutionized pediatric ophthalmology and has had a significant impact on ophthalmology in general. The Leica Envisu C2300 hand-held OCT allows to…
From Organs to Tissues to Cells: Analyzing 3D Specimens with Widefield Microscopy
Obtaining high-quality data and images from thick 3D samples is challenging using traditional widefield microscopy because of the contribution of out-of-focus light. In this webinar, Falco Krüger…
How does an Automated Rating Solution for Steel Inclusions Work?
The rating of non-metallic inclusions (NMIs) to determine steel quality is critical for many industrial applications. For an efficient and cost-effective steel quality evaluation, an automated NMI…
Perform Microscopy Analysis for Pathology Ergonomically and Efficiently
The main performance features of a microscope which are critical for rapid, ergonomic, and precise microscopic analysis of pathology specimens are described in this article. Microscopic analysis of…
How to improve your Biomarker Discovery Workflow with Laser Microdissection
Biomarkers can be used as indicators of certain diseases, such as cancer. The tumor microenvironment moved into the spotlight in this concern. It is in close interaction with the tumor itself.…
How to Conduct Standard-Compliant Analysis of Non-Metallic Inclusions in Steel
This webinar will provide an overview of the significance of non-metallic inclusions in steel and outline the important global standards for rating the quality of steel and difficulties that arise in…
Plastic & Reconstructive Surgery: Why Use a Microscope
Plastic and Reconstructive Surgery procedures can be delicate. Visualization solutions play an essential role, allowing to perform the surgery in the best conditions. And more and more plastic…
Minimally Invasive Spine Surgery: Improving Precision and Accuracy with Microscopes
Spine surgery is extremely delicate and requires extensive training and experience. Innovative visualization technologies can also help achieve better outcomes allowing to see more and have a clearer…
Neurosurgery with Heads-up Display
In the following video interviews Prof. Dr. Raphael Guzman, Vice Chairman of the Department of Neurosurgery at the University Hospital in Basel, Switzerland, talks about his experience in heads-up…
Workflows and Instrumentation for Cryo-electron Microscopy
Cryo-electron microscopy is an increasingly popular modality to study the structures of macromolecular complexes and has enabled numerous new insights in cell biology. In recent years, cryo-electron…
An Introduction to Computational Clearing
Many software packages include background subtraction algorithms to enhance the contrast of features in the image by reducing background noise. The most common methods used to remove background noise…
Factors to Consider When Selecting a Research Microscope
An optical microscope is often one of the central devices in a life-science research lab. It can be used for various applications which shed light on many scientific questions. Thereby the…
Challenges Faced When Manually Rating Non-Metallic Inclusions (NMIs) to Determine Steel Quality
Rapid, accurate, and reliable rating of non-metallic inclusions (NMIs) is instrumental for the determination of steel quality. This article describes the challenges that arise from manual NMI rating,…
How Can Immunofluorescence Aid Virology Research?
Modern virology research has become as crucial now as ever before due to the global COVID-19 pandemic. There are many powerful technologies and assays that virologists can apply to their research into…
