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Unlocking Insights in Complex and Dense Neuron Images Guided by AI

Explore how Aivia 12 Image Analysis Software, powered by artificial intelligence (AI), can improve soma detection by as much as 46% - Webinar on demand

THY1-EGFP labeled neurons in mouse brain processed using the PEGASOS 2 tissue clearing method, imaged on a Leica confocal microscope. Neurons were traced using Aivia’s 3D Neuron Analysis – FL recipe. Image credit: Hu Zhao, Chinese Institute for Brain Research. Neurons_in_mouse_brain_with_Aivia_3D_Neuron_Analysis.jpg

3D morphological analysis of neurons often requires using different imaging modalities, capturing multiple types of neurons and inspecting neurons in a range of densities. These complexities make it difficult for neuroscientists to understand the morphology of neurons and remain a time-consuming challenge for many researchers.  

About the webinar

Join us and explore how artificial intelligence (AI) can help researchers in complex neuroscience experiments. The latest advancement in Aivia Image Analysis Software, powered by AI, provides improved soma detection, additional flexibility in neuron tracing, 3D spatial measurement capabilities including Sholl analysis and much more. These robust applications combined into a single platform allows researchers to analyze challenging images and unlock insights into new discoveries.

What you will learn in the webinar

Key Learnings

  • Learn how AI can improve soma detection and partitioning in dense neuron images
  • Leverage 3D neuron tracing in Golgi-stained images to streamline your microscopy workflow
  •  Gain deeper insights with advanced charting capabilities and 3D Sholl analysis

Harnessing the power of AI image analysis

The recent advancement of Artificial Intelligence (AI) has presented new opportunities in complex experiments and unlocked insights previously out of reach. By attending this on-demand session, you gain access to the most up-to-date information, valuable insights into best practices, useful tips, and real-world applications of Aivia AI image analysis software.

In this webinar our presenter, Quyen Tran, PhD, highlights new and improved AI features available in our latest release of Aivia. Aivia 12 adds a new option for soma detection within the neuron recipe. This option incorporates the generalist Cellpose algorithm (Stringer, 2021) [1], enabling up to 46% improvement of soma detection in densely populated neuronal images. Additionally, somas within dense soma regions are better partitioned using Cellpose. This release also streamlines AI-enabled 3D tracing of Golgi-stained images using new updates to the neuron analysis workflow. 

Application across multiple disciplines

Aivia has remarkable applications across various research disciplines. When working in a core imaging facility or as an academic investigator in cell biology or neurosciences, increasing the adoption of new technologies to achieve high-quality results is critical for the success of your institution, and for your publishing output. 

Aivia 12 offers advanced features to all researchers to generate more insights. It incorporates new 3D relational measurements that allow you to explore object-to-object relationships such as identifying overlapping objects. Additionally, this release brings interactive plots for data exploration with tools such a Pearson correlation coefficient heat map and violin plots.

AI access for all

In connection with Bioimage.IO model zoo’s mission of making deep learning models more accessible to the bioimaging community, Aivia 12 brings four pre-trained Bioimage.IO deep learning models into the Aivia ecosystem. Drag-and-drop the models into Aivia and combine it with other features of Aivia to power your analysis.  Furthermore, parameter estimation via the Aivia That Learns deep learning model has been iteratively optimized and enhanced making it easier to get to your results faster. 

Aivia makes advanced data analysis accessible for all, with no computer science expertise required. This means the new AI features mentioned above are incorporated so you can use them without coding or setting up Python and CUDA environments. With Aivia, anyone can get started with AI.

Want to learn more? Register below to watch the full webinar presented by Quyen Tran, PhD

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