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Science Lab
Science Lab
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
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![Advancing pediatric brain tumor surgery. Picture copyright: Shutterstock Advancing pediatric brain tumor surgery. Picture copyright: Shutterstock](/fileadmin/_processed_/f/0/csm_Advancing_pediatric_brain_tumor_surgery_shutterstock_3d98b3cb96.jpg)
Advancing Surgery in Pediatric Brain Tumors
Learn how fluorescence-guided surgery supports pediatric brain tumor resection and improves precision through literature review and clinical cases.
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![Phase-contrast image of a MDCK-cell culture and its respective confluency measured by the Mateo TL microscope. Phase-contrast image of a MDCK-cell culture and its respective confluency measured by the Mateo TL microscope.](/fileadmin/_processed_/b/1/csm_Phase-contrast_image_of_a_MDCK-cell_culture_respective_confluency_Mateo_TL_a84aca67c2.jpg)
How to Determine Cell Confluency with a Digital Microscope
This article shows how to measure cell confluency in an easy and consistent way with Mateo TL, increasing confidence in downstream experiments.
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![Microscope image of cultured cells at the bottom of a dish. Microscope image of cultured cells at the bottom of a dish.](/fileadmin/_processed_/f/1/csm_CellCheck-17-cells-grow-divide_9bcd60530d.jpg)
How to do a Proper Cell Culture Quick Check
In order to successfully work with mammalian cell lines, they must be grown under controlled conditions and require their own specific growth medium. In addition, to guarantee consistency their growth…
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![Intensity distribution (arbitrary color coding) of an image of two points where the distance between them corresponds to the Rayleigh criterion. Intensity distribution (arbitrary color coding) of an image of two points where the distance between them corresponds to the Rayleigh criterion.](/fileadmin/_processed_/3/1/csm_Intensity_distribution_Rayleigh_criterion_58ccd036cd.jpg)
Microscope Resolution: Concepts, Factors and Calculation
This article explains in simple terms microscope resolution concepts, like the Airy disc, Abbe diffraction limit, Rayleigh criterion, and full width half max (FWHM). It also discusses the history.
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![Five-color FLIM-STED Five-color FLIM-STED](/fileadmin/_processed_/a/3/csm_5-color_FLIM-STED_9d88340e60.jpg)
Five-color FLIM-STED with One Depletion Laser
Webinar on five-color STED with a single depletion laser and fluorescence lifetime phasor separation.
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![John Hamilton, Bchir, MB, FRCS, Consultant Ear, Nose & Throat Surgeon, Gloucester Royal Hospital. Dr. Hamilton during ontological surgery with his trainees. John Hamilton, Bchir, MB, FRCS, Consultant Ear, Nose & Throat Surgeon, Gloucester Royal Hospital. Dr. Hamilton during ontological surgery with his trainees.](/fileadmin/_processed_/9/a/csm_Dr._Hamilton_during_ontological_surgery_with_his_trainees_eb665aab5f.jpg)
Why 3D Microscope Visualization Enriches Surgical ENT Education
Learn about the benefits of using a Leica surgical microscope with 3D visualization for surgical