Science Lab
Science Lab
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
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Multi-Color Caspase 3/7 Assays with Mica
Caspases are involved in apoptosis and can be utilized to determine if cells are undergoing this programmed cell death pathway in so-called caspase assays. These assays can be run by e.g. flow…
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How To Get Multi Label Experiment Data With Full Spatiotemporal Correlation
This video on demand focuses on the special challenges of live cell experiments. Our hosts Lynne Turnbull and Oliver Schlicker use the example of studying the mitochondrial activity of live cells.…
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Create New Options for Live Cell Imaging
The use of state-of-the-art AI systems is pushing image analysis into a new generation. Challenges like the conflict between imaging power and sample integrity are being overcome with THUNDER’s…
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Improving Ergonomics With a Dental Microscope
Here, we show you how Dr. David Blanc, a dental surgeon and ergonomics consultant, improves physical comfort using a dental microscope with ultra-low binoculars. Through optimized ergonomics, Dr.…
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Using GLOW800 AR in Radial Forearm Flap Free Phalloplasty
In this video, Chief Microsurgeon Professor Küntscher and his team perform a radial forearm free flap phalloplasty and use ICG fluorescence imaging to show the blood flow in the whole flap from the…
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Fast, High-contrast 3D Imaging of Sensory Neurons
This article discusses how fast, high-contrast 3D imaging of dorsal root ganglion (DRG) tissue with a THUNDER Imager Tissue using large volume computational clearing (LVCC) allows sensory neurons to…
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Find Relevant Specimen Details from Overviews
Switch from searching image by image to seeing the full overview of samples quickly and identifying the important specimen details instantly with confocal microscopy. Use that knowledge to set up…
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AI Microscopy Image Analysis – An Introduction
Artificial intelligence-guided microscopy image analysis and visualization is a powerful tool for data-driven scientific discovery. AI can help researchers tackle challenging imaging applications,…
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How to Target Fluorescent Structures in 3D for Cryo-FIB Milling
This article describes the major steps of the cryo-electron tomography workflow including super-resolution cryo-confocal microscopy. We describe how subcellular structures can be precisely located in…