![Science Lab](/fileadmin/_processed_/6/0/csm_lms-sl-header_d2c38d8093.jpg)
Science Lab
Science Lab
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
Filter articles
Tags
Story Type
Products
Loading...
![Preparation of an IC-chip cross section: grinding and polishing of the chip cross section. Preparation of an IC-chip cross section: grinding and polishing of the chip cross section.](/fileadmin/_processed_/3/b/csm_Grinding_polishing_EM_TXP_91d5c1584d.jpg)
Cross-section Analysis for Electronics Manufacturing
This article describes cross-section analysis for electronics concerning quality control and failure analysis of printed circuit boards (PCBs) and assemblies (PCBAs), integrated circuits (ICs), etc.
Loading...
![Murine esophageal organoids (DAPI, Integrin26-AF 488, SOX2-AF568) imaged with the THUNDER Imager 3D Cell Culture. Courtesy of Dr. F.T. Arroso Martins, Tamere University, Finland. Murine esophageal organoids (DAPI, Integrin26-AF 488, SOX2-AF568) imaged with the THUNDER Imager 3D Cell Culture. Courtesy of Dr. F.T. Arroso Martins, Tamere University, Finland.](/fileadmin/_processed_/f/f/csm_THUNDER_Imager_3D_Cell_Culture_Murine-esophageal-organoid_LVCC_9bc587500f.jpg)
How to Get Deeper Insights into your Organoid and Spheroid Models
In this eBook, learn about key considerations for imaging 3D cultures, such as organoids and spheroids, and discover microscopy solutions to shed new insights into dynamic processes in 3D real-time
Loading...
![Water Flea Daphnia imaged by Electron Microscopy. Courtesy of Mag. Dr. Gruber, University of Vienna, Austria. Water Flea Daphnia imaged by Electron Microscopy. Courtesy of Mag. Dr. Gruber, University of Vienna, Austria](/fileadmin/_processed_/e/d/csm_EM_Application_Water_Flea_Daphnia_7abc89f4fb.jpg)
Streamline your EM Sample Preparation Workflow for Biological Applications
Master EM sample preparation, including ultramicrotomy, for life sciences in this expert eBook!
Loading...
![](/fileadmin/_processed_/5/4/csm_Upright_Fluorescence_Microscopy_for_Virus_Replication_Studies_SemrockSlide_4e89c4ef8a.jpg)
Studying Virus Replication with Fluorescence Microscopy
The results from research on SARS-CoV-2 virus replication kinetics, adaption capabilities, and cytopathology in Vero E6 cells, done with the help of fluorescence microscopy, are described in this…
Loading...
![Co-detection of 10 extracellular matrix proteins and 3 topographical tissue landmarks by multiplex immunostaining within a single high-grade fibrous hotspot from a human hepatocellular carcinoma Co-detection of 10 extracellular matrix proteins and 3 topographical tissue landmarks by multiplex immunostaining within a single high-grade fibrous hotspot from a human hepatocellular carcinoma](/fileadmin/_processed_/0/8/csm_Single_high-grade_fibrous_hotspot_from_a_human_hepatocellular_carcinoma_e5541282bd.jpg)
In Situ Identification of Cancer Stem Cell Niches in Hepatocellular Carcinoma
Discover how multiplexed imaging technology uncovers cancer stem cell niches in Hepatocellular Carcinoma using multiplex immunodetection, revealing extracellular matrix dynamics. Explore precise…
Loading...
![Image of a Siemens star, where the diameter of the 1st black line circle is 10 mm and the 2nd is 20 mm, taken via an eyepiece of a M205 A stereo microscope. Image of a Siemens star, where the diameter of the 1st black line circle is 10 mm and the 2nd is 20 mm, taken via an eyepiece of a M205 A stereo microscope. The rectangles represent the field of view (FOV) of a Leica digital camera when installed with various C-mounts (red 0.32x, blue 0.5x, green 0.63x).](/fileadmin/_processed_/7/9/csm_30_000-to1-magnification_2292e8ea90.jpg)
Understanding Clearly the Magnification of Microscopy
To help users better understand the magnification of microscopy and how to determine the useful range of magnification values for digital microscopes, this article provides helpful guidelines.
Loading...
![Fluorescence microscopy image of liver tissue where DNA in the nuclei are stained with Feulgen-pararosanilin and visualized with transmitted green light. Fluorescence microscopy image of liver tissue where DNA in the nuclei are stained with Feulgen-pararosanilin and visualized with transmitted green light.](/fileadmin/_processed_/0/6/csm_Fluorescence_microscopy_image_of_liver_tissue_449f2971ad.jpg)
Epi-Illumination Fluorescence and Reflection-Contrast Microscopy
This article discusses the development of epi-illumination and reflection contrast for fluorescence microscopy concerning life-science applications. Much was done by the Ploem research group…
Loading...
![Esophageal tissue with a squamous cell carcinoma labelled with the 4 biomarkers PanCk, DAPI, NaKATPase, and Vimentin. Esophageal tissue with a squamous cell carcinoma labelled with the 4 biomarkers PanCk, DAPI, NaKATPase, and Vimentin.](/fileadmin/_processed_/7/1/csm_Esophageal_Squamous_Cell_Carcinoma_4_Markers_cb901ea02b.jpg)
Discover how Multiplexed Bioimaging can Advance Cancer Research
Explore multiplexing with up to 60 biomarkers, enabling advanced tumor imaging approaches to gather precise, spatially-resolved single-cell data that helps enhance cancer research and clinical…
Loading...
![Prof. Nikolaos Bechrakis uses the Proveo 8 ceiling mounted microscope with EnFocus intraoperative OCT. Images provided by Prof. Nikolaos Bechrakis. Prof. Nikolaos Bechrakis uses the Proveo 8 ceiling mounted microscope with EnFocus intraoperative OCT. Images provided by Prof. Nikolaos Bechrakis.](/fileadmin/_processed_/7/3/csm_Prof_Bechrakis_uses_Proveo_8_ceiling_mounted_microscope_with_EnFocus_intraoperative_OCT_dad0be1120.jpg)
Posterior Segment Surgery: Benefits of Utilizing Intraoperative OCT
Learn about the value of intraoperative optical coherence tomography in posterior segment surgery to precisely locate, evaluate and manage pathologies.