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Science Lab
Science Lab
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
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![Particles which could be found during cleanliness analysis of parts and components. Particles which could be found during cleanliness analysis of parts and components.](/fileadmin/_processed_/8/f/csm_Particles_found_during_cleanliness_analysis_b09473be0e.jpg)
Cleanliness of Automotive Components and Parts
This article discusses the ISO 16232 standard and VDA 19 guidelines and briefly summarizes the particle analysis methods. They give important criteria for the cleanliness of automotive parts and…
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![](/fileadmin/_processed_/a/6/csm_Micacam-03-picture__8a40730e82.jpg)
How Does The Cytoskeleton Transport Molecules?
VIDEO ON DEMAND - See how 3D cysts derived from MDCK cells help scientists understand how proteins are transported and recycled in tissues and the role of the cytoskeleton in this transport.
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![Mouse whole-mount retina. Image courtesy of the Experimental Ophthalmology Group, University of Murcia, Spain. Mouse whole-mount retina. Image courtesy of the Experimental Ophthalmology Group, University of Murcia, Spain.](/fileadmin/_processed_/4/a/csm_Mouse_whole-mount_retina_Thundered_abe5e38481.jpg)
Fast, High Acuity Imaging and AI-assisted Analysis
The use of state-of-the-art AI systems is pushing image analysis into a new generation. Challenges like the conflict between imaging power and sample integrity are being overcome with THUNDER’s…
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![Developing zebrafish (Danio rerio) embryo, from sphere stage to somite stages. Developing zebrafish (Danio rerio) embryo, from sphere stage to somite stages.](/fileadmin/_processed_/8/f/csm_Developing_Zebrafish_embryo_MicaCam_teaser_62bb968899.jpg)
Studying Early Phase Development of Zebrafish Embryos
VIDEO ON DEMAND - This second edition of MicaCam focuses on combining widefield and confocal imaging to study the early-stage development of zebrafish embryos (Danio rerio), from oocyte to…
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![GLOW800 Augmented Reality fluorescence in Moyamoya disease treatment. Image courtesy of Prof. Dr. Feres Chaddad GLOW800 Augmented Reality fluorescence in Moyamoya disease treatment](/fileadmin/_processed_/b/b/csm_GLOW800_Augmented_Reality_Moyamoya_disease_treatment_5fa6edea9f.jpg)
How AR Helps in the Surgical Treatment of Moyamoya Disease
Moyamoya disease is a rare chronic occlusive cerebrovascular disorder characterized by progressive stenosis in the terminal portion of the internal carotid artery and an abnormal vascular network at…
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![Two-color caspase assay with tile scan Two-color caspase assay with tile scan](/fileadmin/_processed_/c/7/csm_Two-color_caspase_assay_with_tile_scan_2c488fe90e.jpg)
Multi-Color Caspase 3/7 Assays with Mica
Caspases are involved in apoptosis and can be utilized to determine if cells are undergoing this programmed cell death pathway in so-called caspase assays. These assays can be run by e.g. flow…
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![U2OS cells U2OS cells stained with Hoechst for nuclei (blue), MitoTracker green (Mitochondria structure, green) and TMRE (active mitochondria, magenta) and SiR for tubulin (red). Simultaneous acquisition of four channel large area overview using Spiral scan feature using the 10x/1.20 CS2 Water MotCORR objective.](/fileadmin/_processed_/f/0/csm_U2OS_cells_four_channel_Spiral_scan_Mica_673dd1380f.jpg)
How To Get Multi Label Experiment Data With Full Spatiotemporal Correlation
VIDEO ON DEMAND - The first edition of MicaCam focuses on the special challenges of live cell experiments. Our hosts Lynne Turnbull and Oliver Schlicker use the example of studying the mitochondrial…
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![3D reconstruction of an isolated human islet 3D reconstruction of an isolated human islet](/fileadmin/_processed_/d/1/csm_THUNDER-Imager-3D-Cell-Culture_isolated-human-islet_6bcb590f44.jpg)
Create New Options for Live Cell Imaging
The use of state-of-the-art AI systems is pushing image analysis into a new generation. Challenges like the conflict between imaging power and sample integrity are being overcome with THUNDER’s…
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![Dr. Blanc using the M320 dental microscope with ultra-low binoculars Dr. Blanc using the M320 dental microscope with ultra-low binoculars](/fileadmin/_processed_/4/8/csm_M320_dental_microscope_with_ultra-low_binoculars_2c99fb4165.jpg)
Improving Ergonomics With a Dental Microscope
Here, we show you how Dr. David Blanc, a dental surgeon and ergonomics consultant, improves physical comfort using a dental microscope with ultra-low binoculars. Through optimized ergonomics, Dr.…