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Science Lab
Science Lab
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
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![](/fileadmin/_processed_/a/d/csm_thunder-and-aivia-teaser_e1a10860b2.jpg)
Save Time and Effort with AI-assisted Fluorescence Image Analysis
The powerful synergy of THUNDER and Aivia analyze fluorescence images with greater accuracy, even when using low light excitation.
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![Colourised binary mask of a time-lapse microscopy field of view of medium confluency Separation of cells based on their tracking status: A colourised binary mask of a time-lapse microscopy field of view of medium confluency with individual cells highlighted as survivors if they can be tracked since the initial movie frame (cyan), incomers if they migrated into the field of view throughout the movie (yellow) or mistracks if an error occurred in the automated trajectory reconstruction (red).](/fileadmin/_processed_/7/b/csm_Tracking_single_cells_using_deep_learning_teaser_a66bd5e2a9.jpg)
Tracking Single Cells Using Deep Learning
AI-based solutions continue to gain ground in the field of microscopy. From automated object classification to virtual staining, machine and deep learning technologies are powering scientific…
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![Analysis of anatomy and axon orientation of an adult mouse brain tissue with QLIPP. Analysis of anatomy and axon orientation of an adult mouse brain tissue with QLIPP.](/fileadmin/_processed_/c/5/csm_Learning_the_Cellular_Architecture_from_its_Optical_Properties_teaser_4479e6abd5.jpg)
Learning the Cellular Architecture from its Optical Properties
In the last 3 years, microscopists have started to use "AI based" solutions for a wide range of applications, including image acquisition optimization (smart microscopy), object classification, image…
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![Visual inspection of a PCBA with the Ivesta 3 Greenough stereo microscope. Visual inspection of a PCBA with the Ivesta 3 Greenough stereo microscope.](/fileadmin/_processed_/a/a/csm_Ivesta_3_integrated_monitor_users_2_fc7f6bf183.jpg)
How to Select the Right Solution for Visual Inspection
This article helps users with the decision-making process when selecting a microscope as a solution for routine visual inspection. Important factors that should be considered are described.
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![](/fileadmin/_processed_/0/f/csm_Inspiring_Simple_Inspection_teaser_f7bb0e9177.jpg)
How to Use a Digital Microscope to Streamline Inspection Processes
Watch this webinar for inspiration and expert advice on how to make quality control simpler, quicker, and easier. Learn how to perform comprehensive visual inspection, including comparison,…
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![Dynamic Signal Enhancement powered by Aivia: Truly simultaneous multicolor imaging of live cells (U2OS) in 3D Dynamic Signal Enhancement powered by Aivia: Truly simultaneous multicolor imaging of live cells (U2OS) in 3D](/fileadmin/_processed_/b/1/csm_How_Artificial_Intelligence_Enhances_Confocal_Imaging_teaser_b7b1cbed5e.jpg)
Artificial Intelligence and Confocal Microscopy – What You Need to Know
This list of frequently asked questions provides “hands-on” answers and is a supplement to the introductory article about Dynamic Signal Enhancement powered by Aivia "How Artificial Intelligence…
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![Dynamic Signal Enhancement powered by Aivia: Truly simultaneous multicolor imaging of live cells (U2OS) in 3D Dynamic Signal Enhancement powered by Aivia: Truly simultaneous multicolor imaging of live cells (U2OS) in 3D](/fileadmin/_processed_/b/1/csm_How_Artificial_Intelligence_Enhances_Confocal_Imaging_teaser_b7b1cbed5e.jpg)
How Artificial Intelligence Enhances Confocal Imaging
In this article, we show how artificial intelligence (AI) can enhance your imaging experiments. Namely, how Dynamic Signal Enhancement powered by Aivia improves image quality while capturing the…
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![](/fileadmin/_processed_/7/4/csm_Designing_your_Research_Study_with_Multiplexed_IF_Imaging_teaser_8149cd5698.jpg)
Designing your Research Study with Multiplexed IF Imaging
Multiplexed tissue analysis is a powerful technique that allows comparisons of cell-type locations and cell-type interactions within a single fixed tissue sample. It is common for researchers to ask…
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![](/fileadmin/_processed_/9/c/csm_Formulated_product_characterisation_with_SRS_microscopy_teaser_5a89dbb2c3.jpg)
Formulated Product Characterization with SRS Microscopy
Creams, pastes, gels, emulsions, and tablets are ubiquitous across a wide range of manufacturing sectors from pharmaceuticals and consumer health products to agrochemicals and paint. To improve…