![Science Lab](/fileadmin/_processed_/6/0/csm_lms-sl-header_d2c38d8093.jpg)
Science Lab
Science Lab
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
Filter articles
Tags
Story Type
Products
Loading...
![Particulate contamination in between moving metal plates. Particulate contamination in between moving metal plates.](/fileadmin/_processed_/b/d/csm_Particulate_contamination_in_between_moving_metal_plates_2_ec4b8bf9ea.jpg)
Key Factors for Efficient Cleanliness Analysis
An overview of the key factors necessary for technical cleanliness and efficient cleanliness analysis concerning automotive and electronics manufacturing and production is provided in this article.
Loading...
![Microscope equipped with a K7 color CMOS camera for life-science and industry imaging applications. Microscope equipped with a K7 color CMOS camera for life-science and industry imaging applications.](/fileadmin/_processed_/9/e/csm_Microscope_equipped_with_a_K7_color_CMOS_d4485ce44f.jpg)
Technical Terms for Digital Microscope Cameras and Image Analysis
Learn more about the basic principles behind digital microscope camera technologies, how digital cameras work, and take advantage of a reference list of technical terms from this article.
Loading...
![Images of the same area of a processed wafer taken with standard (left) and oblique (right) brightfield illumination using a Leica compound microscope. The defect on the wafer surface is clearly more visible with oblique illumination. Images of the same area of a processed wafer taken with standard (left) and oblique (right) brightfield illumination using a Leica compound microscope. The defect on the wafer surface is clearly more visible with oblique illumination.](/fileadmin/_processed_/9/1/csm_Processed_wafer_standard_and_oblique_brightfield_illumination_fb296b5b5d.jpg)
Rapid Semiconductor Inspection with Microscope Contrast Methods
Semiconductor inspection for QC of materials like wafers can be challenging. Microscope solutions that offer several contrast methods enable fast and reliable defect detection and efficient workflows.
Loading...
![2D slice of colon cancer tissue stained with 30 markers and imaged using the Cell DIVE system. Analysis performed using Aivia 13’s new multiplex cell detection recipe and automatic clustering tool. Each phenotype denoted in a different color. 2D slice of colon cancer tissue stained with 30 markers and imaged using the Cell DIVE system. Analysis performed using Aivia 13’s new multiplex cell detection recipe and automatic clustering tool. Each phenotype denoted in a different color.](/fileadmin/_processed_/4/2/csm_2D_slice_of_colon_cancer_tissue_stained_with_30_markers_Aivia_Cell_DIVE_86e8e2380c.jpg)
Transforming Multiplexed 2D Data into Spatial Insights Guided by AI
Aivia 13 handles large 2D images and enables researchers to obtain deep insights into microenvironment surrounding their phenotypes with millions of detected objects and automatic clustering up to 30…
Loading...
![Applying dispersive viscoelastic to coat the anterior chamber. Image courtesy of Arsham Sheybani, MD, Washington University School of Medicine. Applying dispersive viscoelastic to coat the anterior chamber. Image courtesy of Arsham Sheybani, MD, Washington University School of Medicine.](/fileadmin/_processed_/6/3/csm_Applying_dispersive_viscoelastic_to_coat_the_anterior_chamber_d1c42722e0.jpg)
Dislocated Cataract Angle Closure Aided by Intraoperative OCT
Learn how a dislocated cataract was treated with angle closure assisted by intraoperative OCT to achieve long-term good results without future lens dislocation.
Loading...
![Spheroid stained with Cyan: Dapi nuclear countertain; Green AF488 Involucrin; Orange AF55 Phalloidin Actin; Magenta AF647 CK14. Spheroid stained with Cyan: Dapi nuclear countertain; Green AF488 Involucrin; Orange AF55 Phalloidin Actin; Magenta AF647 CK14.](/fileadmin/_processed_/6/8/csm_Spheroid_stained_with_Cyan_4color_overlay_76cb6e4d04.jpg)
Notable AI-based Solutions for Phenotypic Drug Screening
Learn about notable optical microscope solutions for phenotypic drug screening using 3D-cell culture, both planning and execution, from this free, on-demand webinar.
Loading...
![Hepatocellular Carcinoma with 13 biomarkers shown – Beta-Catenin, CD3D, CD4, CD8a, CD31, CD44, CD163, DAPI, PanCK, PCK26, PD1, SMA, and Vimentin. Hepatocellular Carcinoma with 13 biomarkers shown – Beta-Catenin, CD3D, CD4, CD8a, CD31, CD44, CD163, DAPI, PanCK, PCK26, PD1, SMA, and Vimentin.](/fileadmin/_processed_/5/b/csm_Hepatocellular_Carcinoma_13_Markers_Zoom2_bc27c21cf2.jpg)
Understanding Tumor Heterogeneity with Protein Marker Imaging
Explore tumor heterogeneity and immune cell dynamics. See how quantitative imaging analysis reveals spatial relationships and molecular insights crucial for advancing cancer research and therapeutics.
Loading...
![Adult human Alzheimer’s brain demonstrating a panel of 15 markers. Adult human Alzheimer’s brain demonstrating a panel of 15 markers.](/fileadmin/_processed_/4/9/csm_Adult_human_Alzheimers_brain_68bacde06e.jpg)
The Shape of the Brain: Spatial Biology of Alzheimer’s Disease
Uncover cell identity and brain structure in Alzheimer's disease with Cell DIVE multiplexed imaging, demonstrating how spatial biology can lead to advances in therapy development for…
Loading...
![Dr. Sheybani places the new subconjunctival stent in the anterior chamber. Images courtesy of Arsham Sheybani, MD. Dr. Sheybani places the new subconjunctival stent in the anterior chamber. Images courtesy of Arsham Sheybani, MD.](/fileadmin/_processed_/f/e/csm_Subconjunctival_stent_in_the_anterior_chamber_a134a07957.jpg)
Glaucoma Stent Revision Surgery Guided by Intraoperative OCT
Learn about a glaucoma subconjunctival stent revision guided by intraoperative OCT and the important role it plays to ensure the best outcome.