Science Lab
Science Lab
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
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An Introduction to Fluorescence
This article gives an introduction to fluorescence and photoluminescence, which includes phosphorescence, explains the basic theory behind them, and how fluorescence is used for microscopy.
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How to Image Histological and Fluorescent Samples with One System
VIDEO ON DEMAND - How to image histological and fluorescent samples with one system. FluoSync, the new technology embedded into Mica enables the imaging of both histological staining and fluorescence…
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How to Radically Simplify Workflows in Your Imaging Facility
VIDEO ON DEMAND - How to radically simplify imaging workflows and generate meaningful results with less time and effort using a highly automated microscope that unites widefield and confocal imaging.
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FluoSync - a Fast & Gentle Method for Unmixing Multicolor Images
In this white paper, we focus on a fast and reliable method for obtaining high-quality multiplex images in fluorescence microscopy. FluoSync combines an existing method for hybrid unmixing with…
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Harnessing Microfluidics to Maintain Cell Health During Live-Cell Imaging
VIDEO ON DEMAND - In this webinar on-demand, we will use microfluidics to explore the effect of shear stress on cell morphology, examine the effect of nutrient replenishment on cellular growth during…
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How to Perform Dynamic Multicolor Time-Lapse Imaging
Live-cell imaging sheds light on diverse cellular events. As many of these events have fast dynamics, the microscope imaging system must be fast enough to record every detail. One major advantage of…
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Following Multiple Events during Staurosporine Apoptosis
In this video on demand, we show how adding additional markers to an apoptosis kit can markedly increase the amount of information a researcher can obtain from the same experiment. The simultaneous…
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Golgi Organizational Changes in Response to Cell Stress
In this video on demand, our special guest George Galea from EMBL Heidelberg will look at HeLa Kyoto cells treated with various chemotherapeutic agents to investigate their effect on the Golgi complex…
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AI-Enabled Spatial Analysis of Complex 3D Datasets
This video on demand offers practical advice on the extraction of publication grade insights from microscopy images. Our special guest Luciano Lucas (Leica Microsystems) will illustrate how Mica’s…