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Science Lab
Science Lab
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
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![](/fileadmin/_processed_/7/4/csm_Designing_your_Research_Study_with_Multiplexed_IF_Imaging_teaser_8149cd5698.jpg)
Designing your Research Study with Multiplexed IF Imaging
Multiplexed tissue analysis is a powerful technique that allows comparisons of cell-type locations and cell-type interactions within a single fixed tissue sample. It is common for researchers to ask…
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![Fluorescently stained mouse tibia, imaged with a THUNDER Imager 3D Tissue. Courtesy of Dr. Anjali Kusumbe, University of Oxford, UK.](/fileadmin/academy/2021/Abstracts_Interviews_Webinars/High-resolution_3D_imaging_to_investigate_tissue_ageing_teaser.jpg)
High-resolution 3D Imaging to Investigate Tissue Ageing
Award-winning researcher Dr. Anjali Kusumbe demonstrates age-related changes in vascular microenvironments through single-cell resolution 3D imaging of young and aged organs.
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![](/fileadmin/_processed_/9/c/csm_How_to_successfully_implement_the_Leica_Nano_workflow_teaser_93854cf895.jpg)
How to Successfully Implement Coral Life
The live-cell CLEM workflow allows you to capture dynamic information related to a relevant biological process as it happens and put these observations into their ultrastructural context. The Leica…
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![](/fileadmin/_processed_/d/e/csm_Advancing_Cellular_Ultrastructure_Research_teaser_057c43bdbf.jpg)
Advancing Cellular Ultrastructure Research
Freeze-fracture and freeze-etching are useful tools for studying flexible membrane-associated structures such as tight junctions or the enteric glycocalyx. Freeze-fracture and etching are two…
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![](/fileadmin/_processed_/5/5/csm_Clinical_Symposium_on_OCT-guided_cornea_surgery_teaser_f09075e4a4.jpg)
Clinical Symposium on OCT-guided Cornea Surgery
In this recording Prof. Mehta from Singapore National Eye Centre and Prof. Fontana from Santa Maria
Nuova Hospital in Regio Emilia, Italy, share their expertise on corneal surgery. They present PK,…
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![](/fileadmin/academy/2021/Abstracts_Interviews_Webinars/Optimizing_THUNDER_platform_for_high-content_slide_scanning_teaser.jpg)
Optimizing THUNDER Platform for High-Content Slide Scanning
With rising demand for full-tissue imaging and the need for FL signal quantitation in diverse biological specimens, the limits on HC imaging technology are tested, while user trainability and…
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![](/fileadmin/_processed_/0/2/csm_Parkinson_Header_3-2_66feb4a0b4.jpg)
Visualizing Protein Degradation and Aggregation in the Living Cell
Our guest speaker, Prof Dr Eric Reits, presents his work on neurodegenerative disorders. Reits’ group are experts on the subject of Huntington’s disease and work towards identifying leads for…
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![](/fileadmin/_processed_/3/9/csm_Leica-Nano-Workflow-Teaser_526e63843e.jpg)
Capture life as it happens
With the Leica Nano Workflow, searching for the needle in the haystack is a thing of the past. Take advantage of correlative light and electron microscopy to identify directly the right cell at the…
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![](/fileadmin/_processed_/e/e/csm_Microstructural_Characterization_including_Qualitative_Analysis_6a8fabb779.jpg)
Microstructural Characterization including Compositional Analysis
Leica Microsystems' versatile upright compound microscope, DM6 M, fitted with Laser-Induced Breakdown Spectroscopy module will let you not only analyze metallographically polished samples and conduct…