Envisu R-Class OCT für die präklinische Forschung

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Publications

High-Resolution Optical Coherence Tomography–Guided Donor Tissue Preparation for Descemet Membrane Endothelial Keratoplasty Using the Reverse Big Bubble Technique
Cabot, Florence; Kankariya, Vardhaman P; Ruggeri, Marco; Yoo, Sonia H; Vaddavalli, Pravin K; Parel, Jean-Marie; Kymionis, George D
Cornea. 2014 Apr; 33(4): 428–431 doi:  10.1097/ICO.0000000000000070

Ganglion Cell Layer–Inner Plexiform Layer Thickness and Vision Loss in Young Children With Optic Pathway Gliomas
Gu, Sherry; Glaug, Natalie; Cnaan, Avital; Packer, Roger J; Avery, Robert A;
Investigative Ophthalmology & Visual Science March 2014, Vol.55, 1402-1408. doi:10.1167/iovs.13-13119

Three-Dimensional Assessment of Vascular and Perivascular Characteristics in Subjects with Retinopathy of Prematurity
Maldonado, Ramiro S; Yuan, Eric; Tran-Viet, Du; Rothman, Adam L; Tong, Amy Y; Wallace, David K; Freedman, Sharon F; Toth, Cynthia A;
Ophthalmology. 2014 Jun; 121(6): 1289–1296. doi:10.1016/j.ophtha.2013.12.004

Quantitative classification of Eyes with and without intermediate age-related macular degeneration using optical coherence tomography
Farsiu, Sina; Chiu, Stephanie J; O'Connell, Rachelle V; Folgar, Francisco A; Yuan, Eric; Izatt, Joseph A; Toth, Cynthia A;
Ophthalmology.  2014 Jan; 121 (1): 162–172. DOI: dx.doi.org/10.1016/j.ophtha.2013.07.013

Handheld Optical Coherence Tomography During Sedation in Young Children With Optic Pathway Gliomas
Avery, Robert A; Hwang, Eugene I; Ishikawa, Hiroshi; Acosta, Maria T; Hutcheson, Kelly A; Santos, Domiciano; Zand, Dina J; Kilburn, Lindsay B; Rosenbaum, Kenneth N; Rood, Brian R;
JAMA Ophthalmol. 2014;132(3):265-271. doi:10.1001/jamaophthalmol.2013.7649.

Optical coherence contrast imaging using gold nanorods in living mice eyes
Zerda, Adam; Prabhulkar, Shradha; Perez, Victor L; Ruggeri, Marco; Paranjape, Amit S; Habte, Frezghi; Gambhir, Sanjiv S; Awdeh, Richard M;
Clinical & Experimental Ophthalmology, 43: 358–366. doi: 10.1111/ceo.12299

Gold Nanorods as a Contrast Agent for Doppler Optical Coherence Tomography
Wang, Bo; Kagemann, Larry; Schuman, Joel S; Ishikawa, Hiroshi; Bilonick, Richard A; Ling, Yun; Sigal, Ian A; Nadler, Zach; Francis, Andrew; Sandrian, Michelle G;
PLoS ONE 9(3): e90690. doi:10.1371/journal.pone.0090690

The value of intraoperative optical coherence tomography imaging in vitreoretinal surgery
Ehlers, Justis P; Tao, Yuankai K; Srivastava, Sunil K;
Curr Opin Ophthalmol. 2014 May; 25(3): 221–227. doi:  10.1097/ICU.0000000000000044

Lateral and axial measurement differences between spectral-domain optical coherence tomography systems
Folgar, Francisco A; Yuan, Eric L; Farsiu, Sina; Toth, Cynthia A;
J. Biomed. Opt. 19(1), 016014 (Jan 17, 2014). doi:10.1117/1.JBO.19.1.016014

A Lensing Effect of Inner Retinal Cysts on Images of the Photoreceptor Mosaic
Langlo, Christopher S; Flatter, John A; Dubra, Alfredo; Wirostko, William J; Carroll, Joseph;
Retina, Vol. 34, No. 2 (February 2014): 421-422

Intrasurgical dynamics of macular hole surgery: an assessment of surgery-Induced ultrastructural alterations with intraoperative optical coherence tomography
Ehlers, Justis P; Xu, David; Kaiser, Peter K; Singh, Rishi P; Srivastava, Sunil K;
Retina.See comment in PubMed Commons below2014 Feb;34(2):213-21. doi: 10.1097/IAE.0b013e318297daf3.

Retinal degeneration increases susceptibility to myopia in mice
Park, Hanna; Tan, Christopher C; Faulkner, Amanda; Jabbar, Seema B; Schmid, Gregor; Abey, Jane; Iuvone, P Michael; Pardue, Machelle T;
Mol Vis. 2013; 19: 2068–2079. Published online 2013 Sep 28.

A novel rat contact lens model for Fusarium keratitis
Shousha, Mohamed Abou; Santos, Andrea Rachelle C; Oechsler, Rafael A; Iovieno, Alfonso; Maestre-Mesa, Jorge; Ruggeri, Marco; Echegaray, Jose J; Dubovy, Sander R; Perez, Victor L; Miller, Darlene;
Mol Vis. 2013; 19: 2596–2605. Published online 2013 Dec 27.

Subretinal gene therapy of mice with Bardet-Biedl Syndrome type 1
Seo, Seongjin; Mullins, Robert F; Dumitrescu, Alina V; Bhattarai, Sajag; Gratie, Daniel; Wang, Kai; Stone, Edwin M; Sheffield, Val; Drack, Arlene V;
Invest Ophthalmol Vis Sci. 2013 Sep; 54(9): 6118–6132. doi:  10.1167/iovs.13-11673

Miniature real-time intraoperative forward-imaging optical coherence tomography probe
Joos, Karen M; Shen, Jin-Hui;
Biomed Opt Express. 2013 Aug 1; 4(8): 1342–1350. doi:  10.1364/BOE.4.001342

Ultra High-Resolution Anterior Segment Optical Coherence Tomography in the Diagnosis and Management of Ocular Surface Squamous Neoplasis
Thomas, Benjamin J; Galor, Anat; Nanji, Afshan A; El Sayyad, Fouad; Wang, Jianhua; Dubovy, Sander R; Joag, Madhura G; Karp, Carol L;
Ocul Surf. 2014 Jan; 12(1): 46–58. doi:  10.1016/j.jtos.2013.11.001

Progression of intermediate age-related macular degeneration with proliferation and inner retinal migration of hyperreflective foci
Christenbury, Joseph G; Folgar, Francisco A; O'Connell, Rachelle V; Chiu, Stephanie J; Farsiu, Sina; Toth, Cynthia A;
Ophthalmology. 2013 May;120(5):1038-45. doi: 10.1016/j.ophtha.2012.10.018. Epub 2013 Jan 23.

Spectral-domain optical coherence tomography characteristics of intermediate age-related macular degeneration
Leuschen, Jessica N; Schuman, Stefanie G; Winter, Katrina P; McCall, Michelle N; Wong, Wai T; Chew, Emily Y; Hwang, Thomas; Srivastava, Sunil; Sarin, Neeru; Clemons, Traci;
Ophthalmology. 2013 Jan;120(1):140-50. doi: 10.1016/j.ophtha.2012.07.004. Epub 2012 Sep 8.

Photobiomodulation reduces photoreceptor death and regulates cytoprotection in early states of P23H retinal dystrophy
Kirk, Diana K; Gopalakrishnan, Sandeep; Schmitt, Heather; Abroe, Betsy; Stoehr, Michele; Dubis, Adam; Carroll, Joseph; Stone, Jonathan; Valter, Krisztina; Eells, Janis;
DOI: 10.1117/12.981791 Conference: SPIE BIOS, Volume: 8569

Diurnal Pattern of Tear Osmolarity and Its Relationship to Corneal Thickness and Deswelling
Niimi, Joycelyn; Tan, Bo; Chang, Jenny; Zhou, Yixiu; Ghanekar, Avanti; Wong, Michelle; Lee, Annie; Lin, Meng C;
Cornea. 2013 Oct;32(10):1305-10. doi: 10.1097/ICO.0b013e31829b21d1

Evaluation of central retinal thickness and subfoveal choroidal thickness in normal eyes
LEE, DW; KIM, J; KIM, CG; LEE, TG;
Acta Ophthalmologica. Volume 91, Issue Supplement s252, page 0, August 2013 DOI: 10.1111/j.1755-3768.2013.T015.x

Potential of handheld optical coherence tomography to determine cause of infantile nystagmus in children by using foveal morphology
Lee, Helena; Sheth, Viral; Bibi, Mashal; Maconachie, Gail; Patel, Aarti; McLean, Rebecca J; Michaelides, Michel; Thomas, Mervyn G; Proudlock, Frank A; Gottlob, Irene;
Ophthalmology. 2013 Dec. 120(12):2714–2724 DOI: dx.doi.org/10.1016/j.ophtha.2013.07.018

Preclinical evaluation and intraoperative human retinal imaging with a high-resolution microscope-integrated spectral domain optical coherence tomography device
Hahn, Paul; Migacz, Justin; O'Connell, Rachelle; Day, Shelley; Lee, Annie; Lin, Phoebe; Vann, Robin; Kuo, Anthony; Fekrat, Sharon; Mruthyunjaya, Prithvi;
Retina. 2013 Jul-Aug;33(7):1328-37. doi: 10.1097/IAE.0b013e3182831293.

Racial variation in optic nerve head parameters quantified in healthy newborns by handheld spectral domain optical coherence tomography
Allingham, Michael J; Cabrera, Michelle T; O'Connell, Rachelle V; Maldonado, Ramiro S; Tran-Viet, Du; Toth, Cynthia A; Freedman, Sharon F; El-Dairi, Mays A;
Journal of American Association for Pediatric Ophthalmology and Strabismus. 2013Oct; 17(5):501–506. DOI: ttp://dx.doi.org/10.1016/j.jaapos.2013.06.014

Subclinical Macular Findings in Infants Screened for Retinopathy of Prematurity with Spectral-Domain Optical Coherence Tomography
Dubis, Adam M; Subramaniam, C Devika; Godara, Pooja; Carroll, Joseph; Costakos, Deborah M;
Ophthalmology. 2013 Aug;120(8):1665-71. doi: 10.1016/j.ophtha.2013.01.028. Epub 2013 May 11.

Is Handheld Optical Coherence Tomography Reliable in Infants and Young Children With and Without Nystagmus?
Lee, Helena; Proudlock, Frank; Gottlob, Irene;
Investigative Ophthalmology & Visual Science December 2013, Vol.54, 8152-8159. doi:10.1167/iovs.13-13230

Choroid development and feasibility of choroidal imaging in the preterm and term infants utilizing SD-OCT
Moreno, Tomas A; O'Connell, Rachelle V; Chiu, Stephanie J; Farsiu, Sina; Cabrera, Michelle T; Maldonado, Ramiro S; Tran-Viet, Du; Freedman, Sharon F; Wallace, David K; Toth, Cynthia A;
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 4140-4147. doi:10.1167/iovs.12-11471

Hand-held high-resolution spectral domain optical coherence tomography in retinoblastoma: clinical and morphologic considerations
Rootman, Daniel Benson; Gonzalez, Efren; Mallipatna, Ashwin; VandenHoven, Cynthia; Hampton, Lindsay; Dimaras, Helen; Chan, Helen SL; Gallie, Brenda L; Heon, Elise;
Br J Ophthalmol doi:10.1136/bjophthalmol-2012-302133

Quantitative single and multi-surface clinical corneal topography utilizing optical coherence tomography
McNabb, Ryan P; Kuo, Anthony N; Izatt, Joseph A;
Optics Letters Vol. 38, Issue 8, pp. 1212-1214 (2013)doi: 10.1364/OL.38.001212

Fast acquisition and reconstruction of optical coherence tomography images via sparse representation
Fang, Leyuan; Li, Shutao; McNabb, R; Nie, Qing; Kuo, A; Toth, C; Izatt, Joseph A; Farsiu, Sina;
IEEE Trans Med Imaging.2013 Nov;32(11):2034-49. doi: 10.1109/TMI.2013.2271904.

Correction of Ocular Shape in Retinal Optical Coherence Tomography and Effect on Current Clinical Measures
Kuo, Anthony N; McNabb, Ryan P; Chiu, Stephanie J; El-Dairi, Mays A; Farsiu, Sina; Toth, Cynthia A; Izatt, Joseph A;
American Journal of Ophthalmology. 2013 Aug; Volume 156, Issue 2, Pages 304–311. DOI: dx.doi.org/10.1016/j.ajo.2013.03.012

Outer Retinal Structure Following Closed Globe Blunt Ocular Trauma
Flatter, John; Dubow, Michael; Singh, Ravi; Shah, Nishit; Robison, Scott; Weinberg, David; Stepien, Kimberly; Dubra, Alfredo; Rosen, Richard; Carroll, Joseph;
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 1090. doi:

Dry Age-Related Macular Degeneration: Mechanisms, Therapeutic Targets, and Imaging
Rickman, Catherine Bowes; Farsiu, Sina; Toth, Cynthia A; Klingeborn, Mikael;
Investigative Ophthalmology & Visual Science December 2013, Vol.54, ORSF68-ORSF80. doi:10.1167/iovs.13-12757

Macular morphology and visual acuity in the Comparison of Age-related Macular Degeneration Treatments Trials
Jaffe, Glenn J; Martin, Daniel F; Toth, Cynthia A; Daniel, Ebenezer; Maguire, Maureen G; Ying, Gui-Shuang; Grunwald, Juan E; Huang, Jiayan;
Ophthalmology. 2013 Sep; Volume 120, Issue 9, Pages 1860–1870. Doi:10.1016/j.ophtha.2013.01.073

Characterization of the Choroid-Scleral Junction and Suprachoroidal Layer in Healthy Individuals on Enhanced-Depth Imaging Optical Coherence Tomography
Yiu, Glenn; Pecen, Paula; Sarin, Neeru; Chiu, Stephanie J; Farsiu, Sina; Mruthyunjaya, Prithvi; Toth, Cynthia A;
JAMA Ophthalmol. 2014;132(2):174-181. doi:10.1001/jamaophthalmol.2013.7288.

Fully Automatic Software for Retinal Thickness in Eyes With Diabetic Macular Edema From Images Acquired by Cirrus and Spectralis Systems
Lee, Joo Yong; Chiu, Stephanie J; Srinivasan, Pratul P; Izatt, Joseph A; Toth, Cynthia A; Farsiu, Sina; Jaffe, Glenn J;
Investigative Ophthalmology & Visual Science November 2013, Vol.54, 7595-7602. doi:10.1167/iovs.13-11762

Unprocessed real-time imaging of vitreoretinal surgical maneuvers using a microscope-integrated spectral-domain optical coherence tomography system
Hahn, Paul; Migacz, Justin; O’Connell, Rachelle; Izatt, Joseph A; Toth, Cynthia A;Graefe's Archive for Clinical and Experimental Ophthalmology. January 2013, Volume 251, Issue 1, pp 213-220 

Visualization of real-time intraoperative maneuvers with a microscope-mounted spectral domain optical coherence tomography system
Ehlers, Justis P; Tao, Yuankai K; Farsiu, Sina; Maldonado, Ramiro; Izatt, Joseph A; Toth, Cynthia A;
Retina. 2013 Jan;33(1):232-6. doi: 10.1097/IAE.0b013e31826e86f5.

Photoreceptor proteins initiate microglial activation via toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal
Kohno, Hideo; Chen, Yu; Kevany, Brian M; Pearlman, Eric; Miyagi, Masaru; Maeda, Tadao; Palczewski, Krzysztof; Maeda, Akiko;
The Journal of Biological Chemistry. 2013 May; 288:15326-15341. doi: 10.1074/jbc.M112.448712

Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization
Zhang, Ning; Kolesnikov, Alexander V; Jastrzebska, Beata; Mustafi, Debarshi; Sawada, Osamu; Maeda, Tadao; Genoud, Christel; Engel, Andreas; Kefalov, Vladimir J; Palczewski, Krzysztof;
J Clin Invest. 2013;123(1):121–137. doi:10.1172/JCI66176.

Retinal pigmented epithelial cells obtained from human induced pluripotent stem cells possess functional visual cycle enzymes in vitro and in vivo
Maeda, Tadao; Lee, Mee Jee; Palczewska, Grazyna; Marsili, Stefania; Tesar, Paul J; Palczewski, Krzysztof; Takahashi, Masayo; Maeda, Akiko;
The Journal of Biological Chemistry. 2013 Nov; 288, 34484-34493. doi: 10.1074/jbc.M113.518571

QLT091001, a 9-cis-retinal analog, is well-tolerated by retinas of mice with impaired visual cycles
Maeda, Tadao; Dong, Zhiqian; Jin, Hui; Sawada, Osamu; Gao, Songqi; Utkhede, Deepank; Monk, Wendy; Palczewska, Grazyna; Palczewski, Krzysztof;
Investigative Ophthalmology & Visual Science January 2013, Vol.54, 455-466. doi:10.1167/iovs.12-11152

Synthesis and evaluation of a nanoglobular dendrimer 5-aminosalicylic acid conjugate with a hydrolyzable Schiff base spacer for treating retinal degeneration
Wu, Xueming; Yu, Guanping; Luo, Chengcai; Maeda, Akiko; Zhang, Ning; Sun, Da; Zhou, Zhuxian; Puntel, Anthony; Palczewski, Krzysztof; Lu, Zheng-Rong;
ACS Nano, 2014, 8 (1), pp 153–161. doi: 10.1021/nn4054107

Systems pharmacology identifies drug targets for Stargardt disease–associated retinal degeneration
Chen, Yu; Palczewska, Grazyna; Mustafi, Debarshi; Golczak, Marcin; Dong, Zhiqian; Sawada, Osamu; Maeda, Tadao; Maeda, Akiko; Palczewski, Krzysztof;
J Clin Invest. 2013;123(12):5119-5134. doi:10.1172/JCI69076

Rhodopsin F45L allele does not cause autosomal dominant retinitis pigmentosa in a large Caucasian family
Vincent, Andrea L; Carroll, Joseph; Fishman, Gerald A; Sauer, Alexandra; Sharp, Dianne; Summerfelt, Phyllis; Williams, Vesper; Dubis, Adam M; Kohl, Susanne; Wong, Fulton;
Translational Vision Science & Technology March 2013, Vol.2, 4. doi:10.1167/tvst.2.2.4

Repeatability and reproducibility of choroidal vessel layer measurements in diabetic retinopathy using enhanced depth optical coherence tomography
Sim, Dawn A; Keane, Pearse A; Mehta, Hemal; Fung, Simon; Zarranz-Ventura, Javier; Fruttiger, Marcus; Patel, Praveen J; Egan, Catherine A; Tufail, Adnan;
Investigative Ophthalmology & Visual Science April 2013, Vol.54, 2893-2901. doi:10.1167/iovs.12-11085

X-linked cone dystrophy and colour vision deficiency arising from a missense mutation in a hybrid L/M cone opsin gene
McClements, Michelle; Davies, Wayne IL; Michaelides, Michel; Carroll, Joseph; Rha, Jungtae; Mollon, John D; Neitz, Maureen; MacLaren, Robert E; Moore, Anthony T; Hunt, David M;
Vision Research. 22 March 2013, Volume 80, Pages 41–50. doi:10.1016/j.visres.2012.12.012

Selective cone photoreceptor injury in acute macular neuroretinopathy
Hansen, Sean O; Cooper, Robert F; Dubra, Alfredo; Carroll, Joseph; Weinberg, David V;
Retina. 2013 Sep;33(8):1650-8. doi: 10.1097/IAE.0b013e31828cd03a.

A novel segmentation algorithm for volumetric analysis of macular hole boundaries identified with optical coherence tomography
Xu, David; Yuan, Alex; Kaiser, Peter K; Srivastava, Sunil K; Singh, Rishi P; Sears, Jonathan E; Martin, Daniel F; Ehlers, Justis P;
Investigative Ophthalmology & Visual Science January 2013, Vol.54, 163-169. doi:10.1167/iovs.12-10246

High-resolution images of retinal structure in patients with choroideremia
Syed, Reema; Sundquist, Sanna M; Ratnam, Kavitha; Zayit-Soudry, Shiri; Zhang, Yuhua; Crawford, J Brooks; MacDonald, Ian M; Godara, Pooja; Rha, Jungtae; Carroll, Joseph;
Investigative Ophthalmology & Visual Science February 2013, Vol.54, 950-961. doi:10.1167/iovs.12-10707

Contrast-enhanced intraoperative optical coherence tomography
Ehlers, Justis P; McNutt, Stephen A; Kaiser, Peter K; Srivastava, Sunil K;
Br J Ophthalmol. 2014;98:11 1588-1591doi:10.1136/bjophthalmol-2012-303048

Novel microarchitectural dynamics in rhegmatogenous retinal detachments identified with intraoperative optical coherence tomography
Ehlers, Justis P; Ohr, Matthew P; Kaiser, Peter K; Srivastava, Sunil K;
Retina. 2013 Jul-Aug;33(7):1428-34. doi: 10.1097/IAE.0b013e31828396b7.

Retinal thickness normative data in wild-type mice using customized miniature SD-OCT
Ferguson, Lee R; Dominguez II, James M; Balaiya, Sankarathi; Grover, Sandeep; Chalam, Kakarla V;
PLoS ONE 8(6): e67265. doi:10.1371/journal.pone.0067265