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Leica Microsystems

Leica Microsystems

Leica Microsystems ist ein weltweit führender Hersteller von Mikroskopen und wissenschaftlichen Instrumenten. Im 19. Jahrhundert als Familienunternehmen gegründet, war die Geschichte des Unternehmens auf dem Weg zum Weltkonzern von beispielloser Innovation geprägt.

Die traditionell enge Zusammenarbeit mit der Wissenschaft ist der Schlüssel zur Innovationstradition von Leica Microsystems, die auf die Ideen der Anwender zurückgreift und auf deren Bedürfnisse zugeschnittene Lösungen schafft. Auf globaler Ebene ist Leica Microsystems in drei Divisionen gegliedert, die alle zu den führenden Anbietern in ihrem jeweiligen Bereich gehören: Life Science, Industrie und Medizin.

Das Unternehmen ist in über 100 Ländern mit 6 Produktionsstandorten in 5 Ländern, Vertriebs- und Serviceorganisationen in 20 Ländern und einem internationalen Händlernetz vertreten. Der Hauptsitz des Unternehmens liegt in Wetzlar, Deutschland.

https://www.leica-microsystems.com/de

U2OS cells stained with Hoechst for nuclei (blue), MitoTracker green (Mitochondria structure, green) and TMRE (active mitochondria, magenta) and SiR for tubulin (red). Simultaneous acquisition of four channel large area overview using Spiral scan feature using the 10x/1.20 CS2 Water MotCORR objective.

How To Get Multi Label Experiment Data With Full Spatiotemporal Correlation

VIDEO ON DEMAND - The first edition of MicaCam focuses on the special challenges of live cell experiments. Our hosts Lynne Turnbull and Oliver Schlicker use the example of studying the mitochondrial…
3D reconstruction of an isolated human islet

Create New Options for Live Cell Imaging

The use of state-of-the-art AI systems is pushing image analysis into a new generation. Challenges like the conflict between imaging power and sample integrity are being overcome with THUNDER’s…
Raw widefield and THUNDER image of a mouse dorsal root ganglion with tdTomato (red) expressed in the sensory neurons.

Fast, High-contrast 3D Imaging of Sensory Neurons

This article discusses how fast, high-contrast 3D imaging of dorsal root ganglion (DRG) tissue with a THUNDER Imager Tissue using large volume computational clearing (LVCC) allows sensory neurons to…
Identification of distinct structures_roundworm_Ascaris_female

Find Relevant Specimen Details from Overviews

Switch from searching image by image to seeing the full overview of samples quickly and identifying the important specimen details instantly with confocal microscopy. Use that knowledge to set up…
Image of fixed U2OS cell expressing mEmerald-Tomm20 denoised using a 3D RCAN model trained with matching low and high SNR image pairs acquired on an iSIM system.

AI Microscopy Image Analysis – An Introduction

Artificial intelligence-guided microscopy image analysis and visualization is a powerful tool for data-driven scientific discovery. AI can help researchers tackle challenging imaging applications,…
Correlation of markers in the LM and the FIB image.

How to Target Fluorescent Structures in 3D for Cryo-FIB Milling

This article describes the major steps of the cryo-electron tomography workflow including super-resolution cryo-confocal microscopy. We describe how subcellular structures can be precisely located in…
HeLa cells labeled with dark blue – Hoechst, Nuclei; magenta – MitoTracker Green, Mitochondria; turquoise - Bodipy, lipid droplets. Cells kindly provided by Ievgeniia Zagoriy, Mahamid Group, EMBL Heidelberg, Germany.

Precise 3D Targeting for EM Imaging - Access What Matters

Find out how the seamless cryo-electron tomography workflow Coral Cryo uses confocal super resolution to target your structure of interest more precisely.
Multi-color SRS image of a tri-cellular cancer spheroid

The Potential of Coherent Raman Scattering Microscopy at a Glance

Coherent Raman scattering microscopy (CRS) is a powerful approach for label-free, chemically specific imaging. It is based on the characteristic intrinsic vibrational contrast of molecules in the…
U2OS cells labelled with SiR Actin, TMRE, CellEvent™, and DAPI; 13-hour time-lapse imaging; apoptosis-inducer staurosporine

Simplifying Complex Fluorescence Multiwell Plate Assays

Apoptosis, or programmed cell death, occurs during organism embryo development to eliminate unwanted cells and during healing in adults to rid the body of damaged cells and help prevent cancer.…
[Translate to German:] Formation of 3D spheroids; Time lapse acquisition over 72 hours

Efficient Long-term Time-lapse Microscopy

Bei Experimenten mit Aufnahmen langer Zeitserien von Sphäroiden können sich bestimmte Herausforderungen ergeben. Da die Experimente mehrere Tage dauern können, muss die Probe möglichst lange am Leben…
Documentation of an automotive clutch friction surface with a digital microscope

Verifying Specifications for Auto Parts and Components

During the development and production of automotive parts and components, whether by suppliers or the auto manufacturer, specifications must be met. This goal is important, because the specifications…
Dr. Tawfik with the Proveo 8 surgical microscope.

Dr. Tawfik Shares his Expert View on Direct Horizontal Chopping in Cataract Surgery

It is estimated that nearly 28 million cataract surgery procedures are performed worldwide every year. Phacoemulsification is the most common method used to remove the cataract and chopping maneuvers…
Laboratory

Factors to Consider when Selecting Clinical Microscopes

What matters if you would like to purchase a clinical microscope? Learn how to arrive at the best buying decision from our Science Lab Article.
Histopathological sample, 40x magnification

Clinical Microscopy: Considerations on Camera Selection

The need for images in pathology laboratories has significantly increased over the past few years, be it in histopathology, cytology, hematology, clinical microbiology, or other applications. They…
Operating room, PROVIDO

Free Flap Procedures in Oncological Reconstructive Surgery

Free flap surgery is considered the gold standard for breast, head and neck reconstructions for cancer patients. These procedures, which enable functional and aesthetic rehabilitation, can be quite…

Operative Intervention bei Bogengangsdehiszenz

Minor’s disease, also called Superior Semicircular Canal Dehiscence (SSCD) or Minor’s syndrome, is a rare disorder of the inner ear that affects hearing and balance. The disease is characterized by…

How to Choose a Microscope for Reconstructive Surgery

Plastic and reconstructive surgery requires excellent visualization to repair intricate and fine structures. Oncological reconstructive surgery procedures are among the most delicate, including breast…
Plastic reconstructive surgery with M530 OHX

Advances in Oncological Reconstructive Surgery

Decision making and patient care in oncological reconstructive surgery have considerably evolved in recent years. New surgical assistance technologies are helping surgeons push the boundaries of what…
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