Medizinische Fachgebiete

Medizinische Fachgebiete

Medizinische Fachgebiete

Entdecken Sie eine umfassende Sammlung wissenschaftlicher und klinischer Ressourcen, die speziell für Ärzte im Gesundheitswesen entwickelt wurden, darunter Berichte von Kollegen, klinische Fallstudien und Symposien. Speziell für Neurochirurgen, Augenärzte, plastische und rekonstruktive Chirurgen, HNO-Ärzte und Zahnärzte. Diese Sammlung präsentiert die neuesten Fortschritte in der chirurgischen Mikroskopie. Entdecken Sie, wie modernste chirurgische Technologien wie AR-Fluoreszenz, 3D-Visualisierung und intraoperative OCT-Bildgebung eine sichere Entscheidungsfindung und Präzision bei komplexen Eingriffen ermöglichen.
Micrograph of dinoflagellate cells. Scale bar = 1 µm.

Wie die Analyse von Meeresmikroorganismen durch Hochdruckgefrieren verbessert werden kann

Die ultrastrukturelle Analyse von Umweltproben, hier Dinoflagellaten, bleibt heutzutage eine Herausforderung. Hier zeigen wir, dass die Durchführung von Hochdruckgefrieren (HPF) vor Ort die…

Advancing Cellular Ultrastructure Research

Freeze-fracture and freeze-etching are useful tools for studying flexible membrane-associated structures such as tight junctions or the enteric glycocalyx. Freeze-fracture and etching are two…
Cryo FIB lamella - Overlay of SEM and confocal fluorescence image. Target structure in yeast cells (nuclear pore proteine Nup159-Atg8-split Venus, red) marked by an arrow. Scale bar: 5 µm. Alegretti et al., Nature 586, 796-800 (2020).

Targeting Active Recycling Nuclear Pore Complexes using Cryo Confocal Microscopy

In this article, how cryo light microscopy and, in particular cryo confocal microscopy, is used to improve the reliability of cryo EM workflows is described. The quality of the EM grids and samples is…
Ultramicrotomy; ARTOS 3D

Introduction to Ultramicrotomy

When studying samples, to visualize their fine structure with nanometer scale resolution, most often electron microscopy is used. There are 2 types: scanning electron microscopy (SEM) which images the…
Array tomography image of T-cells in mouse lymph nodes.

High Resolution Array Tomography with Automated Serial Sectioning

The optimization of high resolution, 3-dimensional (3D), sub-cellular structure analysis with array tomography using an automated serial sectioning solution, achieving a high section density on the…

Visualization of DNA Molecules

Precise low angle rotary shadowing with heavy metals (like platinum) can be used in transmission electron microscopy (TEM) to observe molecular details of objects previously absorbed on a thin, low…

Imaging of Host Cell-bacteria Interactions using Correlative Microscopy under Cryo-conditions

Pathogenic bacteria have developed intriguing strategies to establish and promote infections in their respective hosts. Most bacterial pathogens initiate infectious diseases by adhering to host cells…

Brief Introduction to Freeze Fracture and Etching

Freeze fracture describes the technique of breaking a frozen specimen to reveal internal structures. Freeze etching is the sublimation of surface ice under vacuum to reveal details of the fractured…

Brief Introduction to Specimen Trimming

Before ultrathin sectioning a sample with an ultramicrotome it has to be pre-prepared. For this pre-preparation, special attention must be paid to the sample size (size of the section), location of…
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