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Viventis LS1 Live Microscope à feuillet de lumière à double illumination et simple détection

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Remplacé par Viventis LS2 Live
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Functional in toto imaging

This list presents recent publications in the main application areas of light sheet imaging with the Viventis LS1 and LS2 and is updated regularly.

Light sheet microscopy, also known as Selective Plane Illumination Microscopy (SPIM), has emerged as a powerful imaging technique in scientific research, especially for the study of living samples. This non-invasive method combines optical sectioning and low phototoxicity, allowing researchers to visualize biological processes in three dimensions with high spatiotemporal resolution. Over the years, light sheet microscopy has evolved from its early development in the late 1990s to become a cornerstone technique in several fields of study. Light sheet microscopy has transformed our understanding of developmental biology, neurobiology, and cancer research, among others, with unprecedented insights into the dynamic interactions of cells and tissues.

Publications by application:

Organoids and spheroids

Topological morphogenesis of neuroepithelial organoids
Ishihara et al.,
Nature Physics 2022 

Multiscale light-sheet organoid imaging framework
de Medeiros et al.,
Nature Communication 2022 

Lineage recording in human cerebral organoids
He et al.,
Nature Methods 2021 

Oocytes and Embryos

Mechanism of spindle pole organization and instability in human oocytes
So et al.,
Science 2022 

Aurora kinase A is essential for meiosis in mouse oocytes
Blengini et al.,
Plos Genetics 2021

Fracking and Ostwald ripening position the lumen of the mouse blastocyst
Dumortier et al.,
Science 2019

Zebrafish and other model organisms

Left-right symmetry of zebrafish embryos requires somite surface tension
Naganathan et al.,
Nature 2022 

Deconstructing body axis morphogenesis in zebrafish embryos using robot-assisted tissue micromanipulation
Ozelci et al.,
Nature Communications 2022 

By year of publication:

2024 [LS2]

Open-top multi sample dual-view light-sheet microscope for live imaging of large multicellular systems
Moos et al.,
Nature Methods 2024

2024 [LS1]

LiverZap: a chemoptogenetic tool for global and locally restricted hepatocyte ablation to study cellular behaviours in liver regeneration
Ambrosio et al.,
Development 2024

Cell-autonomous generation of the wave pattern within the vertebrate segmentation clock
Rohde et al.,
Elife 2024 

2023 [LS1]

Integrating single-cell imaging and RNA sequencing datasets links differentiation and morphogenetic dynamics of human pancreatic endocrine progenitors
Beydag-Tasöz et al.,
Developmental Cell 2023 

CHK1-CDC25A-CDK1 regulate cell cycle progression and protect genome integrity in early mouse embryos
Knoblochova et al.,
Embo Reports 2023 

Actin-driven chromosome clustering facilitates fast and complete chromosome capture in mammalian oocytes
Harasimov et al.,
Nature Cell Biology 2023 

The nuclear to cytoplasmic ratio drives cellularization in the close animal relative Sphaeroforma arctica
Olivetta et al.,
Current Biology 2023 

Cell fragmentation in mouse preimplantation embryos induced by ectopic activation of the polar body extrusion pathway
Pelzer et al.,
Embo Journal 2023 

Inverse blebs operate as hydraulic pumps during mouse blastocyst formation
Schliffka et al.,
bioRvix 2023 

Morphodynamics of human early brain organoid development
Jain et al.,
bioRvix 2023 

2022 [LS1]

Deconstructing body axis morphogenesis in zebrafish embryos using robot-assisted tissue micromanipulation
Ozelci et al.,
Nature Communications 2022 

Topological morphogenesis of neuroepithelial organoids
Ishihara et al.,
Nature Physics 2022 

Multiscale light-sheet organoid imaging framework
de Medeiros et al.,
Nature Communication 2022 

Left-right symmetry of zebrafish embryos requires somite surface tension
Naganathan et al.,
Nature 2022 

Mechanism of spindle pole organization and instability in human oocytes
So et al.,
Science 2022 

2021 [LS1]

Cell fate coordinates mechano-osmotic forces in intestinal crypt formation
Yang et al.,
Nature cell Biology 2021 

Lineage recording in human cerebral organoids
He et al.,
Nature Methods 2021 

Tissue Engineering with Mechanically Induced Solid-Fluid Transitions
Mailand et al.,
Ad. Materials 2021 

Aurora kinase A is essential for meiosis in mouse oocytes
Blengini et al.,
Plos Genetics 2021

2020 [LS1]

Embryonic organoids recapitulate early heart organogenesis
Rossi et al.,
Cell Stem Cell 2020 

2019 [LS1] 

Self-organization and symmetry breaking in intestinal organoids development
Serra et al.,
Nature 2019

Fracking and Ostwald ripening position the lumen of the mouse blastocyst
Dumortier et al.,
Science 2019

Primed Track, high-fidelity lineage tracing in mouse pre-implantation embryos using primed conversion of photoconvertible proteins
Welling et al.,
Elife 2019.

Mitochondria in Embryogenesis: An Organellogenesis Perspective
Arribat et al.,
Frontiers in Cell and Developmental Biology 2019.

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