Sciences de la vie | Apprendre et partager | Leica Microsystems

Sciences de la vie

Sciences de la vie

C'est ici que vous pourrez développer vos connaissances, vos capacités de recherche et les applications pratiques de la microscopie dans divers domaines scientifiques. Apprenez à obtenir une visualisation précise, à interpréter les images et à faire progresser la recherche. Trouvez des informations pertinentes sur la microscopie avancée, les techniques d'imagerie, la préparation des échantillons et l'analyse des images. Les sujets abordés comprennent la biologie cellulaire, les neurosciences et la recherche sur le cancer, en mettant l'accent sur les applications et les innovations de pointe.

Micrograph of dinoflagellate cells. Scale bar = 1 µm.

How Marine Microorganism Analysis can be Improved with High-pressure Freezing

In this application example we showcase the use of EM-Sample preparation with high pressure freezing, freeze substiturion and ultramicrotomy for marine biology focusing on ultrastructural analysis of…

C. elegans adult hermaphrodite gonades acquired using THUNDER Imager. Staining: blue - DAPI (nucleus), green - SP56 (sperm), red - RME-2 (oocyte), magenta - PGL-1 (RNA + protein granules). Image courtesy of Prof. Dr. Christian Eckmann, Martin Luther University, Halle, Germany.

Life Science Research: Which Microscope Camera is Right for You?

Deciding which microscope camera best fits your experimental needs can be daunting. This guide presents the key factors to consider when selecting the right camera for your life science research.

[Translate to french:] Stereo microscopes are often considered the workhorses of laboratories and production sites.

Key Factors to Consider When Selecting a Stereo Microscope

This article explains key factors that help users determine which stereo microscope solution can best meet their needs, depending on the application.

Brain organoid section (DAPI) acquired using THUNDER Imager Live Cell. Image courtesy of Janina Kaspar and Irene Santisteban, Schäfer Lab, TUM.

Imaging Organoid Models to Investigate Brain Health

Imaging human brain organoid models to study the phenotypes of specialized brain cells called microglia, and the potential applications of these organoid models in health and disease.

In vivo imaging of a mouse pial and cortical vasculature through a glass window (ROSAmT/mG::Pdgfb-CreERT2 mouse meningeal and cortical visualization following tamoxifen induction and craniotomy). Courtesy: Thomas Mathivet, PhD

Windows on Neurovascular Pathologies

Discover how innate immunity can sustain deleterious effects following neurovascular pathologies and the technological developments enabling longitudinal studies into these events.

Strain from using a microscope can lead to musculoskeletal pain.

Microscope Ergonomics

This article explains microscope ergonomics and how it helps users work in comfort, enabling consistency and efficiency. Learn how to set up the workplace to keep good posture when using a microscope.

Lifetime-based multiplexing in live cells using TauSeparation. Mammalian cells expressing LifeAct-GFP (ibidi GmbH) and labelled with MitoTracker Green. Acquisition with one detector, intensity information shown in grey. The two markers can be separated using lifetime information: LifeAct-GFP (cyan), MitoTracker Green (magenta). Image acquired with STELLARIS 5.

The Power of Reproducibility, Collaboration and New Imaging Technologies

In this webinar you willl learn what impacts reproducibility in microscopy, what resources and initiatives there are to improve education and rigor and reproducibility in microscopy and how…

Branched organoid growing in collagen where the Nuclei are labeled blue. To detect the mechanosignaling process, the YAP1 is labeled green.

Examining Developmental Processes In Cancer Organoids

Interview: Prof. Bausch and Dr. Pastucha, Technical University of Munich, discuss using microscopy to study development of organoids, stem cells, and other relevant disease models for biomedical…

Mouse cortical neurons. Transgenic GFP (green). Image courtesy of Prof. Hui Guo, School of Life Sciences, Central South University, China

How Microscopy Helps the Study of Mechanoceptive and Synaptic Pathways

In this podcast, Dr Langenhan explains how microscopy helps his team to study mechanoceptive and synaptic pathways, their challenges, and how they overcome them.