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Spatial Analysis of Neuroimmune Interactions in Alzheimer’s Disease
Alzheimer’s disease (AD) is a complex neurodegenerative disorder characterized by neurofibrillary tangles, β-amyloid plaques, and neuroinflammation. These dysfunctions trigger or are exacerbated by…
A Guide to Spatial Biology
What is spatial biology, and how can researchers leverage its tools to meet the growing demands of biological questions in the post-omics era? This article provides a brief overview of spatial biology…
Probing Human Alzheimer's Cortical Section using Spatial Multiplexing
Alzheimer’s disease (AD) is the most common neurodegenerative disease and is characterized by the progressive decline of cognitive function. Spatial profiling of AD brain may reveal cellular…
How Efficient is your 3D Organoid Imaging and Analysis Workflow?
Organoid models have transformed life science research but optimizing image analysis protocols remains a key challenge. This webinar explores a streamlined workflow for organoid research, starting…
How did Laser Microdissection enable Pioneering Neuroscience Research?
Dr. Marta Paterlini, a Senior Scientist at the Karolinska Institute, shares her experience of using laser microdissection (LMD) in groundbreaking research into adult human neurogenesis and offers…
AI-Powered Multiplexed Image Analysis to Explore Colon Adenocarcinoma
In this application note, we demonstrate a spatial biology workflow via an AI-powered multiplexed image analysis-based exploration of the tumor immune microenvironment in colon adenocarcinoma.
A Meta-cancer Analysis of the Tumor Spatial Microenvironment
Learn how clustering analysis of Cell DIVE datasets in Aivia can be used to understand tissue-specific and pan-cancer mechanisms of cancer progression
Mapping the Landscape of Colorectal Adenocarcinoma with Imaging and AI
Discover deep insights in colon adenocarcinoma and other immuno-oncology realms through the potent combination of multiplexed imaging of Cell DIVE and Aivia AI-based image analysis
Spatial Architecture of Tumor and Immune Cells in Tumor Tissues
Dig deep into the spatial biology of cancer progression and mouse immune-oncology in this poster, and learn how tumor metabolism can effect immune cell function.
Transforming Multiplexed 2D Data into Spatial Insights Guided by AI
Aivia 13 handles large 2D images and enables researchers to obtain deep insights into microenvironment surrounding their phenotypes with millions of detected objects and automatic clustering up to 30…
Exploring Subcellular Spatial Phenotypes with SPARCS
Discover spatially resolved CRISPR screening (SPARCS), a platform for microscopy-based genetic screening for spatial subcellular phenotypes at the human genome scale.
Unlocking Insights in Complex and Dense Neuron Images Guided by AI
The latest advancement in Aivia AI image analysis software provides improved soma detection, additional flexibility in neuron tracing, 3D relational measurement including Sholl analysis and more.
What are the Challenges in Neuroscience Microscopy?
eBook outlining the visualization of the nervous system using different types of microscopy techniques and methods to address questions in neuroscience.
AI Microscopy Enables the Efficient Detection of Rare Events
Localization and selective imaging of rare events is key for the investigation of many processes in biological samples. Yet, due to time constraints and complexity, some experiments are not feasible…
Deep Visual Proteomics Provides Precise Spatial Proteomic Information
Despite the availability of imaging methods and mass spectroscopy for spatial proteomics, a key challenge that remains is correlating images with single-cell resolution to protein-abundance…
AI-Enabled Spatial Analysis of Complex 3D Datasets
This video on demand offers practical advice on the extraction of publication grade insights from microscopy images. Our special guest Luciano Lucas (Leica Microsystems) will illustrate how Mica’s…
Fast, High Acuity Imaging and AI-assisted Analysis
The use of state-of-the-art AI systems is pushing image analysis into a new generation. Challenges like the conflict between imaging power and sample integrity are being overcome with THUNDER’s…
Create New Options for Live Cell Imaging
The use of state-of-the-art AI systems is pushing image analysis into a new generation. Challenges like the conflict between imaging power and sample integrity are being overcome with THUNDER’s…
AI Microscopy Image Analysis – An Introduction
Artificial intelligence-guided microscopy image analysis and visualization is a powerful tool for data-driven scientific discovery. AI can help researchers tackle challenging imaging applications,…
Multicolor 4D Super Resolution Light Sheet Microscopy
The AI Microscopy Symposium offers a unique forum for discussing the latest AI-based technologies and tools in the field of microscopy and biomedical imaging. In this scientific presentation, Yuxuan…
Accurately Analyze Fluorescent Widefield Images
The specificity of fluorescence microscopy allows researchers to accurately observe and analyze biological processes and structures quickly and easily, even when using thick or large samples. However,…
Applying AI and Machine Learning in Microscopy and Image Analysis
Prof. Emma Lundberg is a professor in cell biology proteomics at KTH Royal Institute of Technology, Sweden. She is also the director of the Cell Atlas, an integral part of the Swedish-based Human…
Using Machine Learning in Microscopy Image Analysis
Recent exciting advances in microscopy technologies have led to exponential growth in quality and quantity of image data captured in biomedical research. However, analyzing large and increasingly…
The AI-Powered Pixel Classifier
Achieving reproducible results manually requires expertise and is tedious work. But now there is a way to overcome these challenges by speeding up this analysis to extract the real value of the image…
Simplifying the Cancer Biology Image Analysis Workflow
As cancer biology data sets grow, so do the challenges in microscopy image analysis. Aivia experts cover how to overcome these challenges with AI.
Examining Critical Developmental Events in High-Definition
Extended live cell imaging of embryo development requires a delicate balance between light exposure, temporal resolution and spatial resolution to maintain cells’ viability. Compromises between the…
Observing Complex Cellular Interactions at Multiple Scales
Learn how to observe challenging cellular interactions with easy to deploy object detection and relationship measurements.
Accelerating Neuron Image Analysis with Automation
The ability to examine complex neural processes relies on the accurate reconstruction of neuronal networks at scale. Most data extraction methods in neuroscience research are time-consuming and…
Save Time and Effort with AI-assisted Fluorescence Image Analysis
The powerful synergy of THUNDER and Aivia analyze fluorescence images with greater accuracy, even when using low light excitation.
Tracking Single Cells Using Deep Learning
AI-based solutions continue to gain ground in the field of microscopy. From automated object classification to virtual staining, machine and deep learning technologies are powering scientific…
Learning the Cellular Architecture from its Optical Properties
In the last 3 years, microscopists have started to use "AI based" solutions for a wide range of applications, including image acquisition optimization (smart microscopy), object classification, image…
AI in Microscopy Webinar
We demonstrate residual channel attention networks for restoring and enhancing volumetric time-lapse (4D) fluorescence microscopy data.
応用分野
細胞生物学
ヒトの健康と病気を細胞ベースで理解することを目的として研究を行う場合、関心のある細胞の構造および分子の詳細から対象の細胞を研究することが重要です。 その結果、細胞生物学における顕微鏡はかってないほどに重要なツールとなり、構造環境内で試料を詳細に調査したり、細胞内小器官や高分子を分析したりすることができます。 細胞生物学イメージングは、さまざまな光電子相関顕微鏡を使用して行われます。…
