インダストリー

産業分野における効率的な検査、最適化されたワークフロー、人間工学に基づく快適性に焦点を当てた詳細な記事やウェビナーをぜひご覧ください。品質管理、材料解析における顕微鏡検査など、幅広いトピックを取り上げています。製造工程の精度と効率を向上させる技術や、最先端技術の活用について、貴重な知見を得ることができます。

Improvement of Metallic Thin Films for HR-SEM by Using DC Magnetron Sputter Coater

Preparation techniques, like several kinds of coating methods play an important role for high resolution scanning electron microscopy (HR-SEM). Nonconductive sample like biological and synthetic…

Imaging of Host Cell-bacteria Interactions using Correlative Microscopy under Cryo-conditions

Pathogenic bacteria have developed intriguing strategies to establish and promote infections in their respective hosts. Most bacterial pathogens initiate infectious diseases by adhering to host cells…

From Light to Mind: Sensors and Measuring Techniques in Confocal Microscopy

This article outlines the most important sensors used in confocal microscopy. By confocal microscopy, we mean "True Confocal Scanning", i.e. the technique that illuminates and measures one single…

Workflows & Protocols: How to Use a Leica Laser Microdissection System and Qiagen Kits for Successful RNA Analysis

Laser Microdissection (LMD) allows isolating individual cells or chromosomes and is a well established technique for sample preparation prior downstream analysis of the nucleic acid content via PCR or…

Schematic graph of the light path in a Spalt-Ultramikroskop.

Confocal and Light Sheet Imaging

Optical imaging instrumentation can magnify tiny objects, zoom in on distant stars and reveal details that are invisible to the naked eye. But it notoriously suffers from an annoying problem: the…

Universal PAINT – Dynamic Super-Resolution Microscopy

Super-resolution microscopy techniques have revolutionized biology for the last ten years. With their help cellular components can now be visualized at the size of a protein. Nevertheless, imaging…

Immersion Freezing for Cryo-Transmission Electron Microscopy: Applications

A well established usage case for cryo-TEM is three-dimensional reconstruction of isolated macromolecules, virus particles, or filaments. On one hand, these approaches are based on averaging of…

Immersion Freezing for Cryo-Transmission Electron Microscopy: Fundamentals

The high vacuum required in a transmission electron microscope (TEM) greatly impairs the ability to study specimens naturally occurring in an aqueous phase: exposing "wet" specimens to a pressure…

Video Tutorials: Filling and Assembling of Different Carriers for High-Pressure Freezing

High pressure freezing (HPF) is a cryo-fixation method primarily for biological samples, but also for a variety of non-biological materials. It is a technique that yields optimal preservation in many…